DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bem46 and Acot4

DIOPT Version :9

Sequence 1:	NP_477372.1	Gene:	Bem46 / 44441	FlyBaseID:	FBgn0025109	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001102910.1	Gene:	Acot4 / 681337	RGDID:	1596753	Length:	421	Species:	Rattus norvegicus

Alignment Length:	236	Identity:	52/236 - (22%)
Similarity:	88/236 - (37%)	Gaps:	69/236 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 MVEYR-----GYGLST---------GVPTERGLVTDARAAIDYLHTR--HDLDHSQ-----LILF 184
            ::|||     |:|.:|         .:|.|..::     .:||....  :.|.|.:     :.|.
  Rat   170 LLEYRASLLAGHGFATLALAFYGFEDLPKEFNVI-----EVDYFEEAVCYMLQHPKVKGPDIGLL 229

  Fly   185 GRSLGGAVVVDVAADTVYGQKLMCAIVENTFSS----------IPEMAVELVHPAVKY--IPNLL 237
            |.|||..|.: :.|..:.......:|..:.||.          ||.:..:|....|.:  |.:::
  Rat   230 GLSLGADVCL-IMASFLKNVSATVSINGSAFSGNRYIHYKQTMIPPLGHDLRRTKVAFSGILDIV 293

  Fly   238 -FKN------KYHSMSKIGKCSVPFLFISGLADNLVPPRMMRALYTKC--------GSEIKRLLE 287
             .:|      :..||..|.|...|.||::|..|:.    ....|||:.        |.|..:::.
  Rat   294 DIRNDAVGGCENPSMIPIEKAKGPILFVAGQDDHC----WRSELYTQIASERLQAHGKERPQIIS 354

  Fly   288 FPGGSHNDTWIVDGYYQAIGGFLAELQQQPLLKAPEKSNVW 328
            :||..|   :|...|:        .:....|.|...|:.||
  Rat   355 YPGTGH---YIEPPYF--------PMCPASLHKIVNKAVVW 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bem46	NP_477372.1	FrsA	72..305	CDD:223999	47/211 (22%)
Bem46	NP_477372.1	Abhydrolase_5	110..294	CDD:289465	44/200 (22%)
Acot4	NP_001102910.1	Bile_Hydr_Trans	17..137	CDD:282610
Acot4	NP_001102910.1	BAAT_C	203..412	CDD:285986	44/203 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900