DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bem46 and BAAT

DIOPT Version :9

Sequence 1:	NP_477372.1	Gene:	Bem46 / 44441	FlyBaseID:	FBgn0025109	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001121082.1	Gene:	BAAT / 570	HGNCID:	932	Length:	418	Species:	Homo sapiens

Alignment Length:	377	Identity:	68/377 - (18%)
Similarity:	105/377 - (27%)	Gaps:	161/377 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LPKSRGVGVGVLAAFLLCFIFYYFYGGYMTLALFAGIILLIFYYAQDLLLYH--PDLPANSRIYI 70
            ||...|:..||:..|          ||...|..|...:|....:|...|.||  .|||..
Human   153 LPPGEGLFPGVIDLF----------GGLGGLLEFRASLLASRGFASLALAYHNYEDLPRK----- 202

  Fly    71 PIPTMHNLPHITVSIKTPDDVTLHAFWVTQPEERSKSSPTLLYFHGNAGNMGHRMQNVWG----- 130
                    |.:|                           .|.||. .|.|...|...|:|
Human   203 --------PEVT---------------------------DLEYFE-EAANFLLRHPKVFGSGVGV 231

  Fly   131 --IYHHLHCNVLMVEY----------RGYGLSTGVPTERGLVTDARAAIDYLHTRHDLDHSQLIL 183
              :...:...:.|..|          .|.....|:|           .:.:......|.||..::
Human   232 VSVCQGVQIGLSMAIYLKQVTATVLINGTNFPFGIP-----------QVYHGQIHQPLPHSAQLI 285

  Fly   184 FGRSLGGAVVVDVAADTVYGQKLMCAIVE--NTFSSIPEMAVELVHPAVKYIPNLLFKNKYHSMS 246
            ...:||                    ::|  .||.:....|.:.:.|
Human   286 STNALG--------------------LLELYRTFETTQVGASQYLFP------------------ 312

  Fly   247 KIGKCSVPFLFISGLADNLVPPRMMRALYTKCGSEIKR-------LLEFPGGSHNDTWIVDGYYQ 304
             |.:....||||.|..|..:   ..:|...:...::||       ||.:||..|    :::..|.
Human   313 -IEEAQGQFLFIVGEGDKTI---NSKAHAEQAIGQLKRHGKNNWTLLSYPGAGH----LIEPPYS 369

  Fly   305 AI-------------GGFLAELQQQPLLKAPEKSNVWVELE-----HKIIDV 338
            .:             ||       :.:..|..:.:.|.|::     |.|.||
Human   370 PLCCASTTHDLRLHWGG-------EVIPHAAAQEHAWKEIQRFLRKHLIPDV 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bem46	NP_477372.1	FrsA	72..305	CDD:223999	41/258 (16%)
Bem46	NP_477372.1	Abhydrolase_5	110..294	CDD:289465	37/209 (18%)
BAAT	NP_001121082.1	Bile_Hydr_Trans	14..140	CDD:377407
BAAT	NP_001121082.1	BAAT_C	207..412	CDD:370148	45/269 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900