DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bem46 and abhd13

DIOPT Version :9

Sequence 1:	NP_477372.1	Gene:	Bem46 / 44441	FlyBaseID:	FBgn0025109	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001032774.1	Gene:	abhd13 / 561333	ZFINID:	ZDB-GENE-051120-54	Length:	337	Species:	Danio rerio

Alignment Length:	297	Identity:	135/297 - (45%)
Similarity:	189/297 - (63%)	Gaps:	10/297 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LAAFLLCFIFYYFYGGYMTLALFAGIILLIFYYAQDLLLYHPDLPANSRIYIPIPTMHNLPHITV 83
            |.|.:|.|   :.|||::.|.|....:..|.|..||:|||.||.|::||:|:|:||  .:||..|
Zfish    30 LLALILTF---HLYGGFVLLGLILASLAGILYKFQDVLLYFPDQPSSSRLYVPMPT--GIPHENV 89

  Fly    84 SIKTPDDVTLHAFWVTQPEERSKSSPTLLYFHGNAGNMGHRMQNVWGIYHHLHCNVLMVEYRGYG 148
            .|:|.|.:.|:...:....|....:||:|||||||||:|||:.|...:..:|..||::|:|||||
Zfish    90 YIRTKDGIRLNLILLRYTGENPAGAPTILYFHGNAGNIGHRVPNALLMLVNLKANVVLVDYRGYG 154

  Fly   149 LSTGVPTERGLVTDARAAIDYLHTRHDLDHSQLILFGRSLGGAVVVDVAADTVYGQKLMCAIVEN 213
            .|.|.|:|.||..||.|.:||:.||.|:|.::::||||||||||.:.:|:...:  ::...:|||
Zfish   155 KSEGDPSEDGLYQDAEATLDYVMTRPDIDKTKVVLFGRSLGGAVAIRLASCNPH--RVAAIMVEN 217

  Fly   214 TFSSIPEMAVEL--VHPAVKYIPNLLFKNKYHSMSKIGKCSVPFLFISGLADNLVPPRMMRALYT 276
            ||.|||.||..|  ..| ::|:|...:|||:.|...:..|.:|.||||||:|.|:||.||:.||.
Zfish   218 TFLSIPHMAATLFSFFP-MRYLPLWCYKNKFLSYRHVVPCRMPSLFISGLSDQLIPPVMMKQLYE 281

  Fly   277 KCGSEIKRLLEFPGGSHNDTWIVDGYYQAIGGFLAEL 313
            ...|..|||..||.|:|||||...||:.|:..|:.||
Zfish   282 LSPSRTKRLAIFPEGTHNDTWQCQGYFSALEQFMKEL 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bem46	NP_477372.1	FrsA	72..305	CDD:223999	108/234 (46%)
Bem46	NP_477372.1	Abhydrolase_5	110..294	CDD:289465	90/185 (49%)
abhd13	NP_001032774.1	FrsA	<114..320	CDD:223999	102/208 (49%)
abhd13	NP_001032774.1	Abhydrolase_5	116..299	CDD:289465	90/185 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574693
Domainoid	1	1.000	120	1.000	Domainoid score	I5733
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6716
Inparanoid	1	1.050	255	1.000	Inparanoid score	I3160
OMA	1	1.010	-	-		QHG54637
OrthoDB	1	1.010	-	-		D1036130at2759
OrthoFinder	1	1.000	-	-		FOG0004924
OrthoInspector	1	1.000	-	-		oto41483
orthoMCL	1	0.900	-	-		OOG6_101827
Panther	1	1.100	-	-	LDO	PTHR12277
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R134
SonicParanoid	1	1.000	-	-		X3471
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800