DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bem46 and bem46

DIOPT Version :9

Sequence 1:	NP_477372.1	Gene:	Bem46 / 44441	FlyBaseID:	FBgn0025109	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_595609.1	Gene:	bem46 / 2540264	PomBaseID:	SPBC32H8.03	Length:	299	Species:	Schizosaccharomyces pombe

Alignment Length:	283	Identity:	111/283 - (39%)
Similarity:	161/283 - (56%)	Gaps:	8/283 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 YGGYMTLALFAGIILLIFYYA-QDLLLYHPDLPANSRIYIPIPTMHNLPHITVSIKTPDDVTLHA 95
            |.|..:||:  .:|.|.|.|. |..|:|....|..||..:|.|...|:.:..:.::|.|.|||.:
pombe    15 YSGMASLAV--TLIALGFLYKYQKTLVYPSAFPQGSRENVPTPKEFNMEYERIELRTRDKVTLDS 77

  Fly    96 FWVTQPEERSKSSPTLLYFHGNAGNMGHRMQNVWGIYHHLHCNVLMVEYRGYGLSTGVPTERGLV 160
            :.:.| .|..:|.|||||||.||||||||:......|..|:.||.::.|||||.|||.|:|.||.
pombe    78 YLMLQ-SESPESRPTLLYFHANAGNMGHRLPIARVFYSALNMNVFIISYRGYGKSTGSPSEAGLK 141

  Fly   161 TDARAAIDYLHTRHDLDHSQLILFGRSLGGAVVVDVAADTVYGQKLMCAIVENTFSSIPEMAVEL 225
            .|::.|::||........::::::|:|:||||.:.:.|..  ..::...|:||||:||.:| :..
pombe   142 IDSQTALEYLMEHPICSKTKIVVYGQSIGGAVAIALTAKN--QDRISALILENTFTSIKDM-IPT 203

  Fly   226 VHPAVKYIPNLLFKNKYHSMSKIGKC-SVPFLFISGLADNLVPPRMMRALYTKCGSEIKRLLEFP 289
            |.|....|.:......:.|..:|.|. .:|.||:||..|.:|||..|..|:..|||..|:...||
pombe   204 VFPYGGSIISRFCTEIWSSQDEIRKIKKLPVLFLSGEKDEIVPPPQMVLLFGLCGSAKKKFHSFP 268

  Fly   290 GGSHNDTWIVDGYYQAIGGFLAE 312
            ..:||||.:.|||:|.|..||||
pombe   269 KCTHNDTCLGDGYFQVIADFLAE 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bem46	NP_477372.1	FrsA	72..305	CDD:223999	90/233 (39%)
Bem46	NP_477372.1	Abhydrolase_5	110..294	CDD:289465	72/184 (39%)
bem46	NP_595609.1	FrsA	7..292	CDD:223999	111/283 (39%)
bem46	NP_595609.1	Abhydrolase_5	91..273	CDD:289465	72/184 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	72	1.000	Domainoid score	I2590
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6716
Inparanoid	1	1.050	186	1.000	Inparanoid score	I1071
OMA	1	1.010	-	-		QHG54637
OrthoFinder	1	1.000	-	-		FOG0004924
OrthoInspector	1	1.000	-	-		oto101880
orthoMCL	1	0.900	-	-		OOG6_101827
Panther	1	1.100	-	-	LDO	PTHR12277
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R134
SonicParanoid	1	1.000	-	-		X3471
TreeFam	1	0.960	-	-
	14	13.860