DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bem46 and Acnat1

DIOPT Version :9

Sequence 1:	NP_477372.1	Gene:	Bem46 / 44441	FlyBaseID:	FBgn0025109	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	XP_006537902.1	Gene:	Acnat1 / 230161	MGIID:	2140197	Length:	430	Species:	Mus musculus

Alignment Length:	264	Identity:	60/264 - (22%)
Similarity:	96/264 - (36%)	Gaps:	81/264 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 TLLYFHGNA---------GNMGHRMQNVWGIYHHLHCNVLM----VEYRGYG-LSTGVPTERGLV 160
            :||..||.|         .::..::|.|...|.....|.|:    ::..|.| :||....|.||
Mouse   193 SLLASHGFAVLALAYFAYKDLPEKLQEVDLEYFEEAANFLLSHPKIQQPGIGVISTSKGAEIGL- 256

  Fly   161 TDARAAIDYLHTRHDLDHSQLILFGRSLGGAVVVDVAADTV-----YGQKLMCAIVENTFSSIPE 220
                |...||        .|:|       ..|.::.|..|.     | |.|:...::   .::..
Mouse   257 ----AMACYL--------KQVI-------ATVCINGATTTTAVPLRY-QDLVVTPIQ---QALER 298

  Fly   221 MAVELVHPAV------KYIPNLLFKNKYHSMSKIGKCSVPFLFISGLADNLVPPRM--MRAL--Y 275
            |.|. |..||      :|:.|   ||    :..:.|.....|||.|..|.|:..::  .||:  .
Mouse   299 MEVH-VSGAVCFRHTTQYLQN---KN----ILPVEKAQGKILFIVGENDELLDSKLHAQRAMDRL 355

  Fly   276 TKCGSEIKRLLEFPGGSHNDTWIVDGYYQAIGGFLAELQQQPLLKAP------------EKSNVW 328
            .:.|....|:|.:||..|    :::..|..    |.....||:|..|            .:.:.|
Mouse   356 RRHGRSSGRMLAYPGAGH----LIEPPYSP----LCFASWQPVLGRPMCFGGDLMAHAAAQEHSW 412

  Fly   329 VELE 332
            .|::
Mouse   413 REIQ 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bem46	NP_477372.1	FrsA	72..305	CDD:223999	53/223 (24%)
Bem46	NP_477372.1	Abhydrolase_5	110..294	CDD:289465	51/212 (24%)
Acnat1	XP_006537902.1	Bile_Hydr_Trans	29..154	CDD:377407
Acnat1	XP_006537902.1	BAAT_C	221..425	CDD:370148	53/236 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900