DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bem46 and Acot6

DIOPT Version :9

Sequence 1:	NP_477372.1	Gene:	Bem46 / 44441	FlyBaseID:	FBgn0025109	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_766168.1	Gene:	Acot6 / 217700	MGIID:	1921287	Length:	419	Species:	Mus musculus

Alignment Length:	225	Identity:	49/225 - (21%)
Similarity:	86/225 - (38%)	Gaps:	64/225 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 PTLLYFHGNAGNM-GHRMQNVWGIYHHLHCNVLMVEYRGYGLSTGVPTERGLVTDARAAIDY--- 169
            |.::..:|:.|.: .||...:.|  |..  .||.:.|..:   ..:|..   ::|.|  ::|
Mouse   158 PGIIDLYGSIGGLCEHRASLLAG--HGF--AVLALAYFQF---EDLPEN---LSDVR--LEYFEE 210

  Fly   170 ---LHTRH-DLDHSQLILFGRSLGGAVVVDVAA---DTVYGQKLMCAIVENTFSSIPEMAVELVH 227
               |..|| .:....:.|.|.|.|..:.:.:||   |.:....|:.|.|.||.  :|....:|
Mouse   211 ALALMLRHPQVKGPNIGLIGVSKGADLCLSMAAFLKDNITATVLINACVANTL--VPLYYKDL-- 271

  Fly   228 PAVKYIPNL---LFKNK------------------YHSMSKIGKCSVPFLFISGLADNLVPPRMM 271
                ::|.|   ..|||                  :.|:..:.|...||||:.|:.|:    ...
Mouse   272 ----FVPELGCDQTKNKSGLMDLRDMWNNPLEEPNHQSLIPLEKAQGPFLFLVGMDDH----NWK 328

  Fly   272 RALYTK--C------GSEIKRLLEFPGGSH 293
            ..:|.:  |      |.:..:::.:|...|
Mouse   329 SDVYARIACERLQAHGKDRPQIIYYPETGH 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bem46	NP_477372.1	FrsA	72..305	CDD:223999	49/225 (22%)
Bem46	NP_477372.1	Abhydrolase_5	110..294	CDD:289465	48/224 (21%)
Acot6	NP_766168.1	Bile_Hydr_Trans	17..137	CDD:282610
		Aes	83..374	CDD:223730	49/225 (22%)
		BAAT_C	203..410	CDD:285986	37/170 (22%)
		Microbody targeting signal. /evidence=ECO:0000255	417..419
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900