DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bem46 and Abhd17a

DIOPT Version :9

Sequence 1:	NP_477372.1	Gene:	Bem46 / 44441	FlyBaseID:	FBgn0025109	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_663396.1	Gene:	Abhd17a / 216169	MGIID:	106388	Length:	310	Species:	Mus musculus

Alignment Length:	218	Identity:	62/218 - (28%)
Similarity:	100/218 - (45%)	Gaps:	26/218 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 TLLYFHGNAGNMGHRMQNVWGIYHHLHCNVLMVEYRGYGLSTGVPTERGLVTDARAAIDYLHTRH 174
            |:|:.||||.::|.......|:...:.||:...:|.|||:|:|.|:|:.|..|..||...|.||:
Mouse   113 TVLFSHGNAVDLGQMCSFYVGLGTRIGCNIFSYDYSGYGISSGRPSEKNLYADIDAAWQALRTRY 177

  Fly   175 DLDHSQLILFGRSLGGAVVVDVAADTVYGQKLMCAIVENTFSSIPEMAVELVHPAVK------YI 233
            .:....:||:|:|:|....||:|:      :..||.|  ...|.....:.:..|..|      ..
Mouse   178 GISPDSIILYGQSIGTVPTVDLAS------RYECAAV--VLHSPLTSGMRVAFPDTKKTYCFDAF 234

  Fly   234 PNLLFKNKYHSMSKIGKCSVPFLFISGLADNLVPPRMMRALYTKCGSEIKRLLEFPGGSHNDTWI 298
            ||:         .|:.|.:.|.|.|.|..|.::......|||.:|...::.|. ..|..|||..:
Mouse   235 PNI---------EKVSKITSPVLIIHGTEDEVIDFSHGLALYERCPKAVEPLW-VEGAGHNDIEL 289

  Fly   299 VDGYYQAIGGFLAELQQQPLLKA 321
            ...|.:.:..|::  |:.|..:|
Mouse   290 YSQYLERLRRFIS--QELPSQRA 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bem46	NP_477372.1	FrsA	72..305	CDD:223999	58/200 (29%)
Bem46	NP_477372.1	Abhydrolase_5	110..294	CDD:289465	54/189 (29%)
Abhd17a	NP_663396.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	38..61
Abhd17a	NP_663396.1	FrsA	<113..305	CDD:223999	60/211 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810