DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bem46 and Acot3

DIOPT Version :9

Sequence 1:	NP_477372.1	Gene:	Bem46 / 44441	FlyBaseID:	FBgn0025109	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_599007.1	Gene:	Acot3 / 171281	MGIID:	2159619	Length:	432	Species:	Mus musculus

Alignment Length:	181	Identity:	37/181 - (20%)
Similarity:	59/181 - (32%)	Gaps:	71/181 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 LHAFWVTQPEERSKSSPTLLYFHGNAGNMGHRMQNVWGIY--HHLHCNVLMVEYRGYGLSTGVP- 154
            :|||....|   ::.:||::            ::...|..  ..:|..|       .||:...|
Mouse     1 MHAFTTQNP---NRMAPTVI------------LEPAGGCLCDQPVHIAV-------RGLAPEQPV 43

  Fly   155 TERGLVTDARAAIDYLHTRHDLD-HSQLIL-----FGRSLGG------------------AVVVD 195
            |.|.::.|.:.|:...|.|:..| |.:|.|     .|.|..|                  .:..|
Mouse    44 TLRSVLRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRD 108

  Fly   196 VAADTVY------------GQKLMCAIVENTFSSIPEMAVELVHPAVKYIP 234
            |....|.            ||:|..|:.|..|.:          |.|:.:|
Mouse   109 VQTPFVVELEVLDGHEPDGGQRLARAVHERHFMA----------PGVRRVP 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bem46	NP_477372.1	FrsA	72..305	CDD:223999	37/181 (20%)
Bem46	NP_477372.1	Abhydrolase_5	110..294	CDD:289465	32/164 (20%)
Acot3	NP_599007.1	Bile_Hydr_Trans	28..148	CDD:282610	29/136 (21%)
		Abhydrolase	148..>264	CDD:304388	1/2 (50%)
		BAAT_C	214..423	CDD:285986
		Microbody targeting signal. /evidence=ECO:0000255	430..432
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900