DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bem46 and Acot2

DIOPT Version :9

Sequence 1:	NP_477372.1	Gene:	Bem46 / 44441	FlyBaseID:	FBgn0025109	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_598949.3	Gene:	Acot2 / 171210	MGIID:	2159605	Length:	453	Species:	Mus musculus

Alignment Length:	220	Identity:	43/220 - (19%)
Similarity:	76/220 - (34%)	Gaps:	75/220 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 AIDYLHTRHDLDHSQLILFGRSLGG---------------AVVVD--VAA---------DTVYGQ 204
            |::||.:..::....:.|.|.|.||               |||::  |||         :|:...
Mouse   252 AVNYLRSHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTISYKDETIPPV 316

  Fly   205 KLMCAIVENTFSSIPEMAVELVHPAV---KYIPNLLFKNKYHSMSKIGKCSVPFLFISGLADN-- 264
            .|:...|:.|...:.::...|..|.|   .:||             :.:....|||:.|..|:
Mouse   317 SLLRNQVKMTKDGLLDVVEALQSPLVDKKSFIP-------------VERSDTTFLFLVGQDDHNW 368

  Fly   265 ---LVPPRMMRALYTKCGSEIKRLLEFPGGSHNDTWIVDGYYQ--------------AIGGFLAE 312
               .....:.:.|... |.|..:::.:|...|   :|...|:.              ..||
Mouse   369 KSEFYADEISKRLQAH-GKEKPQIICYPAAGH---YIEPPYFPLCSAGMHLLVGANITFGG---- 425

  Fly   313 LQQQPLLKAPEKSNVWVELE---HK 334
               :|...|..:.:.|.:|:   ||
Mouse   426 ---EPRAHAVAQVDAWQQLQTFFHK 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bem46	NP_477372.1	FrsA	72..305	CDD:223999	35/186 (19%)
Bem46	NP_477372.1	Abhydrolase_5	110..294	CDD:289465	32/161 (20%)
Acot2	NP_598949.3	Bile_Hydr_Trans	58..178	CDD:282610
		Abhydrolase	186..>298	CDD:304388	11/45 (24%)
		BAAT_C	244..451	CDD:285986	43/220 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900