DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mEFTu1 and mIF2

DIOPT Version :9

Sequence 1:	NP_001163144.1	Gene:	mEFTu1 / 44438	FlyBaseID:	FBgn0024556	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_651621.2	Gene:	mIF2 / 43382	FlyBaseID:	FBgn0039588	Length:	696	Species:	Drosophila melanogaster

Alignment Length:	276	Identity:	90/276 - (32%)
Similarity:	118/276 - (42%)	Gaps:	56/276 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LLAAPRTGNM-QQYLREYANEKKVF-ERTKPHCNVGTI-GHVDHGKTTLTAAITKVLADKQLAES 114
            ::|.|...|. :|..|:.|...... |..:|...|.|: ||||||||||..::..  ||....|
  Fly   130 VVATPEETNADEQKERDVAPRPPAAPELLQPRPPVVTVMGHVDHGKTTLLDSLRG--ADVAAGE- 191

  Fly   115 KKYNEIDNAPEEKARGITINVAHVEYQTETRHYGH----TDCPGHADYIKNMITGTAQMDGAILV 175
                         |.|||   .|:...|.|...|.    .|.||||.:......|....|..:||
  Fly   192 -------------AGGIT---QHIGAFTVTLENGERVTFLDTPGHAAFSAMRARGAVATDIIVLV 240

  Fly   176 VAATDGAMPQTREHMLLAKQIGIDHIVVFINKVDAADEEMVDLVEMEIREL------LTEMGYDG 234
            |||.||.|.||||.:.|||:..:. |:|.:||:|..:..    :|...|||      |.|.|.|.
  Fly   241 VAAEDGVMAQTREVIQLAKEAQVP-IIVALNKIDKPEAN----IEKSKRELAQMGLALEEHGGDV 300

  Fly   235 DKIPVVKGSALCALEDKSPEIGKEAILKLLQEVDSFIPTPVRELDKPFLLPVENVY----SIPGR 295
            ..||:   |||           |...|:||.|..|...|.:.....|..| ||.:.    :.|.|
  Fly   301 QVIPI---SAL-----------KGTNLELLAEAVSTQATLMGLKADPTGL-VEGIVVESKTDPRR 350

  Fly   296 GTVVTGRLERGVVKKG 311
            |.:.|..:.||.::||
  Fly   351 GKLSTAIVSRGTLRKG 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu1	NP_001163144.1	PRK00049	73..463	CDD:234596	84/255 (33%)
		EF_Tu	81..274	CDD:206671	70/203 (34%)
		EFTU_II	282..368	CDD:293898	11/34 (32%)
		mtEFTU_III	371..462	CDD:294005
mIF2	NP_651621.2	InfB	158..689	CDD:223606	83/248 (33%)
		IF2_eIF5B	163..327	CDD:206674	70/201 (35%)
		IF2_mtIF2_II	336..431	CDD:293903	11/32 (34%)
		IF-2	482..575	CDD:288813
		mtIF2_IVc	593..680	CDD:293893
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464554
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840