DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mEFTu1 and mEFTu2

DIOPT Version :9

Sequence 1:	NP_001163144.1	Gene:	mEFTu1 / 44438	FlyBaseID:	FBgn0024556	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_610288.1	Gene:	mEFTu2 / 35681	FlyBaseID:	FBgn0033184	Length:	456	Species:	Drosophila melanogaster

Alignment Length:	421	Identity:	217/421 - (51%)
Similarity:	301/421 - (71%)	Gaps:	14/421 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 WQRNGLLAAPRTGNMQQYLREYANEKKVFERTKPHCNVGTIGHVDHGKTTLTAAITKVLADKQLA 112
            |....|||.....|....|||.           |||||||||||||||||||||||::.:.|.||
  Fly    34 WTGTRLLATSADKNPAPGLREL-----------PHCNVGTIGHVDHGKTTLTAAITRIQSQKGLA 87

  Fly   113 ESKKYNEIDNAPEEKARGITINVAHVEYQTETRHYGHTDCPGHADYIKNMITGTAQMDGAILVVA 177
            |...|::||.||||||||||||..|:.|.|..|.|.|||||||||||||||:|.:||||||||||
  Fly    88 EYLSYDQIDRAPEEKARGITINACHIGYSTTERTYAHTDCPGHADYIKNMISGASQMDGAILVVA 152

  Fly   178 ATDGAMPQTREHMLLAKQIGIDHIVVFINKVDAADEEMVDLVEMEIRELLTEMGYDGDKIPVVKG 242
            ||||.|||||||:|||||:||..|:|||||.|..|:|:::|||:|:||:|::.|:||...||:.|
  Fly   153 ATDGQMPQTREHLLLAKQVGIQRIIVFINKADLVDQEVLELVEIEMREMLSDFGFDGVNSPVICG 217

  Fly   243 SALCALEDKSPEIGKEAILKLLQEVDSFIPTPVRELDKPFLLPVENVYSIPGRGTVVTGRLERGV 307
            |||.||.:...|.|..:|.|||::.||:||||.|::..||:||::|.:::|||||||.|.::||.
  Fly   218 SALLALREDKSEFGVPSIEKLLEQCDSYIPTPQRDISSPFILPIDNAFTVPGRGTVVVGTIKRGT 282

  Fly   308 VKKGMECEFVGYNKVLKSTVTGVEMFHQILEEAQAGDQLGALVRGVKRDDIKRGMVMCKPGSVKA 372
            :.:..:.:.:|:|:.||::::.:::|.:.:.:||||:.:|||:||:|...::|||::|..||...
  Fly   283 IPRNADADLLGFNQNLKTSISDIQIFRKSVPQAQAGENVGALLRGIKISAVERGMLLCATGSEDI 347

  Fly   373 LDQLEAQVYILSKDEGGRTKPFMS-FIQLQMFSRTWDCAVQVQI-PDKEMVMPGEDTKLILRLIR 435
            .:..|..:|:||:.||||.||.:| :|| |:||:||:...::.| |.:.|:||||..::.:.|:|
  Fly   348 SNHFEGSMYLLSRAEGGRVKPMLSKYIQ-QLFSQTWNVPARIDIVPSEAMLMPGEHGQVRVTLLR 411

  Fly   436 PMVLEQGQRFTLRDGNLTLGTGVVTSTLPPL 466
            .||:..||.||:|:...|:.||:||..||.|
  Fly   412 KMVMTPGQAFTIRENGATVATGMVTQRLPSL 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu1	NP_001163144.1	PRK00049	73..463	CDD:234596	206/391 (53%)
		EF_Tu	81..274	CDD:206671	128/192 (67%)
		EFTU_II	282..368	CDD:293898	33/85 (39%)
		mtEFTU_III	371..462	CDD:294005	39/92 (42%)
mEFTu2	NP_610288.1	PRK00049	53..437	CDD:234596	207/395 (52%)
		EF_Tu	56..249	CDD:206671	128/192 (67%)
		EFTU_II	257..343	CDD:293898	33/85 (39%)
		mtEFTU_III	347..437	CDD:294005	38/90 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464542
Domainoid	1	1.000	254	1.000	Domainoid score	I62
eggNOG	1	0.900	-	-		E1_COG0050
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S366
OMA	1	1.010	-	-		QHG28594
OrthoDB	1	1.010	-	-		D298219at33208
OrthoFinder	1	1.000	-	-		FOG0002097
OrthoInspector	1	1.000	-	-		mtm1013
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43721
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	10	9.810