DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec13 and AT3G01340

DIOPT Version :9

Sequence 1:	NP_001287480.1	Gene:	Sec13 / 44437	FlyBaseID:	FBgn0024509	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_001030616.1	Gene:	AT3G01340 / 821216	AraportID:	AT3G01340	Length:	302	Species:	Arabidopsis thaliana

Alignment Length:	307	Identity:	140/307 - (45%)
Similarity:	199/307 - (64%)	Gaps:	26/307 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QEIDTEHEDMVHHAALDFYGLLLATCSSDGSVRI--FHSRKNNKALAELKGHQGPVWQVAWAHPK 68
            |:|:|.|.|.:|...:|:||..:||.|||.:::|  ..:...::.||.|.||:||||||||||||
plant     4 QKIETGHSDTIHDVVMDYYGKRVATASSDCTIKITGVSNSGGSQHLATLTGHRGPVWQVAWAHPK 68

  Fly    69 FGNILASCSYDRKVIVWKSTTPRDWTKLYEYSNHDSSVNSVDFAPSEYGLVLACASSDGSVSVLT 133
            ||::|||||||.::|:||......||:.:.:::|..||||:.:||.|.||.|||.:|||::||.:
plant    69 FGSLLASCSYDGQIILWKEGNQNQWTQAHVFTDHKVSVNSIAWAPHELGLSLACGASDGNISVFS 133

  Fly   134 CNTEYGVWDAKKIPNAHTIGVNAISWCPAQAP---------DPAFDQRVTSRSAAVKRLVSGGCD 189
            ...: |.||..||..||.:||.::||.||..|         ||.:            :|.|||||
plant   134 ARAD-GGWDTTKIDQAHPVGVTSVSWAPATEPGALVSSGMIDPVY------------KLASGGCD 185

  Fly   190 NLVKIWREDNDRWVEE--HRLEAHSDWVRDVAWAPSIGLPRSQIATASQDRHVIVWSSNADLSEW 252
            :.||:|:..|..|..:  ..|..|:||||||||||::|||:|.||:.|:|..||:|:...:..:|
plant   186 STVKVWKFSNGSWKMDCFPALNKHTDWVRDVAWAPNLGLPKSTIASGSEDGKVIIWTIGKEGEQW 250

  Fly   253 TSTVLHTFDDAVWSISWSTTGNILAVTGGDNNVTLWKENTEGQWIRI 299
            ..|||..|...||.:|||.|||:|||:.|:||||:|||:.:|:|.::
plant   251 EGTVLKDFKTPVWRVSWSLTGNLLAVSDGNNNVTVWKESVDGEWEQV 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec13	NP_001287480.1	WD40	10..289	CDD:392136	133/291 (46%)
		WD40 repeat	60..101	CDD:293791	23/40 (58%)
		WD40 repeat	106..148	CDD:293791	21/41 (51%)
		WD40 repeat	155..207	CDD:293791	18/62 (29%)
		WD40 repeat	215..256	CDD:293791	20/40 (50%)
		WD40 repeat	264..290	CDD:293791	17/25 (68%)
AT3G01340	NP_001030616.1	WD40	8..287	CDD:421866	133/291 (46%)
		WD40 repeat	15..54	CDD:293791	13/38 (34%)
		WD40 repeat	59..101	CDD:293791	24/41 (59%)
		WD40 repeat	107..148	CDD:293791	20/41 (49%)
		WD40 repeat	153..207	CDD:293791	19/65 (29%)
		WD40 repeat	214..251	CDD:293791	18/36 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1332
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6479
Inparanoid	1	1.050	309	1.000	Inparanoid score	I747
OMA	1	1.010	-	-		QHG53827
OrthoDB	1	1.010	-	-		D944756at2759
OrthoFinder	1	1.000	-	-		FOG0003364
OrthoInspector	1	1.000	-	-		otm2769
orthoMCL	1	0.900	-	-		OOG6_101941
Panther	1	1.100	-	-	O	PTHR11024
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2253
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840