DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hs2st and Ust

DIOPT Version :9

Sequence 1:	NP_477339.1	Gene:	Hs2st / 44433	FlyBaseID:	FBgn0024230	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_796361.2	Gene:	Ust / 338362	MGIID:	2442406	Length:	407	Species:	Mus musculus

Alignment Length:	293	Identity:	91/293 - (31%)
Similarity:	156/293 - (53%)	Gaps:	24/293 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 LGDSLSPDQHASSTTDDFDFEEHLVVLYNRVPKTGSTSFVNIAYDLCKPNKFHVLHINVTANMH- 113
            ||:|...|.|....:....|...  |:||||.|.||.:.|.:...|.:.:.|::    ||:::|
Mouse    83 LGNSTYLDDHGPPPSKVLPFPSQ--VVYNRVGKCGSRTVVLLLRILSEKHGFNL----VTSDIHN 141

  Fly   114 --VLSLPNQIQFVRNVSRWHEMKPALYHGHMAFLDFSKFQIAHKPIYINLVRKPLDRLVSYYYFL 176
              .|:...|::.::|:|...:  |.|:..|:.||:||:|. ..:|:|||::|.|:.|.:|.|:|.
Mouse   142 KTRLTKNEQMELIKNISTAEQ--PYLFTRHVHFLNFSRFG-GDQPVYINIIRDPVSRFLSNYFFR 203

  Fly   177 RFGD--NYRPNLVR----KKAGNKITFDECVVQKQPDCDPKNMWLQIPFFCGHAAECWEPGSSWA 235
            ||||  ..:.:::|    ::....:..:||:::..|:|....::..||:|||....|.||| .||
Mouse   204 RFGDWRGEQNHMIRTPSMRQEERYLDINECILENYPECSNPRLFYIIPYFCGQHPRCREPG-EWA 267

  Fly   236 LDQAKRNLVNEYFLVGVTEQMYEFVDLLERSLPRIFHGFREHY---HNSNKSHLRVTSSKLPPSE 297
            |::||.|:...:.|||:.|::.:.:.||||.||..|.|....|   .:....::.||..|..||.
Mouse   268 LERAKLNVNENFLLVGILEELEDVLLLLERFLPHYFKGVLSIYKDPEHRKLGNMTVTVRKTVPSP 332

  Fly   298 STIKSIQKTKIWQMENDLYDFALAQFEFNKKKL 330
            ..::.:.:.  .:.|.:.|.:...||...|:||
Mouse   333 EAVQILYQR--MRYEYEFYHYVREQFHLLKRKL 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs2st	NP_477339.1	Sulfotransfer_2	70..325	CDD:281554	82/266 (31%)
Ust	NP_796361.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		Sulfotransfer_2	105..357	CDD:304664	81/263 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	386..407
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3922
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375927at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820