Protein Alignment Hs2st and hst-2

DIOPT Version :10

• Sequence 1: NP_477339.1
• Gene: Hs2st / 44433
• FlyBaseID: FBgn0024230
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_509871.2
• Gene: hst-2 / 181309
• WormBaseID: WBGene00002029
• Length: 324
• Species: Caenorhabditis elegans
• Alignment Length: 284
• Identity: 138/284 - (48%)
• Similarity: 197/284 - (69%)
• Gaps: 10/284 - (3%)

  Fly    74 VVLYNRVPKTGSTSFVN-IAYDLCKPNKFHVLHINVTANMHVLSLPNQIQFVRNVSRWHEMKPAL 137
            :|:|||:||||||:|.| |||||.|.|.|.|||:|:|.|..|:|||:|..||.|::.|.|..||.
 Worm    41 IVIYNRIPKTGSTTFTNAIAYDLYKENGFSVLHVNMTKNRQVMSLPDQYTFVNNITTWTERLPAF 105

  Fly   138 YHGHMAFLDFSKFQIAHKPIYINLVRKPLDRLVSYYYFLRFGDNYRPNLVRKKAGNKITFDECVV 202
            ||||:||:||.:|.||: |||||::|:||:||:|:|||||:|||||..|.|.:|||..|||||..
 Worm   106 YHGHVAFIDFQRFGIAN-PIYINIIREPLERLLSHYYFLRYGDNYRIGLKRSRAGNNETFDECYS 169

  Fly   203 QKQPDCDPKNMWLQIPFFCGHAAECWEPGSSWALDQAKRNLVNEYFLVGVTEQMYEFVDLLERSL 267
            :...|||.|.||:|||:||||...|.|.|:..||..||:|::.:|.|||.|.:|.:.:.|||.::
 Worm   170 RGGKDCDMKQMWIQIPYFCGHYHFCTEVGNPEALRVAKQNVLEKYLLVGTTSRMRDMIALLEVTV 234

  Fly   268 PRIFHGFREHYH--NSNKSHLRVTSSKLPPSESTIKSIQKTKIWQMENDLYDFALAQFEFNKKK- 329
            |..|.|...|:.  ::|::|||.|..|:||::.|:..|::.::::||.:.|||....|:...||
 Worm   235 PDFFKGALGHFDSLDANRAHLRYTKKKIPPNDQTLSMIRRDEVYKMEREFYDFINNLFDAVFKKA 299

  Fly   330 ---LMQPDN--KHVQKFMYEKIRP 348
               :.:.|:  |...::.:|||:|
 Worm   300 TNGISKADDLVKLPLQYHFEKIKP 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hs2st	NP_477339.1	Sulfotransfer_2	70..319	CDD:427369	128/247 (52%)
hst-2	NP_509871.2	Sulfotransfer_2	42..287	CDD:451469	127/245 (52%)