Protein Alignment Hs2st and UST

DIOPT Version :10

• Sequence 1: NP_477339.1
• Gene: Hs2st / 44433
• FlyBaseID: FBgn0024230
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_005706.1
• Gene: UST / 10090
• HGNCID: 17223
• Length: 406
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 95/311 - (30%)
• Similarity: 162/311 - (52%)
• Gaps: 29/311 - (9%)

  Fly    50 LGDSLSPDQHASSTTDDFDFEEHLVVLYNRVPKTGSTSFVNIAYDLCKPNKFHVLHINVTANMH- 113
            ||:|...|.|....:....|...  |:||||.|.||.:.|.:...|.:.:.|::    ||:::|
Human    82 LGNSTYLDDHGPPPSKVLPFPSQ--VVYNRVGKCGSRTVVLLLRILSEKHGFNL----VTSDIHN 140

  Fly   114 --VLSLPNQIQFVRNVSRWHEMKPALYHGHMAFLDFSKFQIAHKPIYINLVRKPLDRLVSYYYFL 176
              .|:...|::.::|:|...:  |.|:..|:.||:||:|. ..:|:|||::|.|::|.:|.|:|.
Human   141 KTRLTKNEQMELIKNISTAEQ--PYLFTRHVHFLNFSRFG-GDQPVYINIIRDPVNRFLSNYFFR 202

  Fly   177 RFGD--NYRPNLVR----KKAGNKITFDECVVQKQPDCDPKNMWLQIPFFCGHAAECWEPGSSWA 235
            ||||  ..:.:::|    ::....:..:||:::..|:|....::..||:|||....|.||| .||
Human   203 RFGDWRGEQNHMIRTPSMRQEERYLDINECILENYPECSNPRLFYIIPYFCGQHPRCREPG-EWA 266

  Fly   236 LDQAKRNLVNEYFLVGVTEQMYEFVDLLERSLPRIFHGFREHY---HNSNKSHLRVTSSKLPPSE 297
            |::||.|:...:.|||:.|::.:.:.||||.||..|.|....|   .:....::.||..|..||.
Human   267 LERAKLNVNENFLLVGILEELEDVLLLLERFLPHYFKGVLSIYKDPEHRKLGNMTVTVKKTVPSP 331

  Fly   298 STIKSIQKTKIWQMENDLYDFALAQFEFNKKKLMQPDNKHVQKFMYEKIRP 348
            ..::.:.:.  .:.|.:.|.:...||...|:|...  ..||.|   ..:||
Human   332 EAVQILYQR--MRYEYEFYHYVKEQFHLLKRKFGL--KSHVSK---PPLRP 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hs2st	NP_477339.1	Sulfotransfer_2	70..319	CDD:427369	80/260 (31%)
UST	NP_005706.1	Sulfotransfer_2	105..350	CDD:427369	80/254 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	387..406