Protein Alignment Cbp80 and STO1

DIOPT Version :9

• Sequence 1: NP_524750.2
• Gene: Cbp80 / 44409
• FlyBaseID: FBgn0022942
• Length: 800
• Species: Drosophila melanogaster
• Sequence 2: NP_013844.2
• Gene: STO1 / 855155
• SGDID: S000004732
• Length: 861
• Species: Saccharomyces cerevisiae
• Alignment Length: 924
• Identity: 183/924 - (19%)
• Similarity: 352/924 - (38%)
• Gaps: 224/924 - (24%)

  Fly     3 RRRAHDTEDEGYDH---RRNKRRRVSENQEIEDRLESLILRVGERSTSSVESNLEGLVSVLEADL 64
            :||....|||.|..   |..||:|:....::...:...|..:|| |..:.|.:::.|...:..:.
Yeast     5 KRRGDFDEDENYRDFRPRMPKRQRIPPVVQLCKEMMPDIRTIGE-SVKAFEDDIKFLSEAIMNEY 68

  Fly    65 G---TFRLKILRILSDCAVRMPEKCTVYTTLVGLLNAKNYKFGGEFVDHMVKTFKESLKMCR--- 123
            |   .|...:|..|:...|..|:|......|..::|:||...|...:::.   |:|..|.|:
Yeast    69 GHEDYFNNALLSTLNAVVVEQPQKQAAIALLTMVVNSKNNVAGKSIINYF---FEELQKWCKQTY 130

  Fly   124 -------------WDAARYSLRFLA---------DLVNCHVISATSLLQLLDTMIDVSNEDTVPQ 166
                         |:..:..||||:         :|:|.:    .||.:|   .|:::|.|...:
Yeast   131 NDEFKSTSNETGPWNKIKLILRFLSILSPMFLVDELINIY----KSLFEL---SIELNNLDPGNR 188

  Fly   167 VRRDWFVFA-VLSTLPWVGRDLYEKKESAL----ESLLLRIEV-YLNKRSKKHHNALRVWSSDAP 225
            |.....::. .|..:|::  ..:.:....|    |.||..:|. ||.|.:  ..|.||.::.:.|
Yeast   189 VPLSEAIYTNTLLNIPYL--FFFNRNNDGLRTKVEELLAYVEQNYLVKTT--DINLLREYNGEPP 249

  Fly   226 HPQEEYLDCLWAQIRK-----LRQDN-----WAEKHIPRPYLVFDSILCEALQHNLPTI------ 274
            :...|.:..:...::|     |.|.|     |  .|:..|. ..|....:||  .||::
Yeast   250 YEMVELVRVVLPNVKKALINNLEQLNELFPDW--NHLLTPQ-TGDEGFNDAL--TLPSVDDLKSF 309

  Fly   275 ---------------VP--------PPHHDNFEYPMPWVVYRMFDYTDCPDGPNLPGAHSIERFL 316
                           .|        |....|||..:|...|....:.|               .:
Yeast   310 VRLNKNFGSVDSMWKTPRYAFHVYLPNSAGNFETVVPISTYAGQLFND---------------II 359

  Fly   317 IEEHLHHIIETYHHERKDCAAQLLSF--------------------------PYKHKIPLEYCIV 355
            |:     ::|:....||:.|.|:::.                          |......:|...:
Yeast   360 ID-----LVESLEFNRKEVARQVITLDLFFKAGIFTEPGESIAQLIATYEENPLAPTFKIEDLAI 419

  Fly   356 EVVFAELFHMPTPRYLDICYGSILIELCKLQPATLPQVLAQATEILFMRIDSMNTSCFDRFVNWF 420
            |.:...:|.:|:.......:.::|:::|:..|..:..|..:|....:..:||::.....|:::||
Yeast   420 ETILGLIFKLPSVSQPFAYFYTLLVDICQNSPKAIAPVFGRAFRFFYSHLDSLDFELKLRYLDWF 484

  Fly   421 SYHLSNFKFTWSWDEWDSCLLLDGEH---PRPKFIQEVLQKCLRL-SYHQRITEMMPTTYAKLIP 481
            |..:|||.|:|.|:||:...:..|::   |:..|.:.::||.||| |....:.:.:|..:.|.:.
Yeast   485 SIQMSNFNFSWKWNEWEDDSIKFGKYFYNPKVNFAKNLIQKELRLTSNFSEVEDSLPQEFTKYLD 549

  Fly   482 LTPVPNYKYANEEAANLPGTTVAHQLV----VAIRQKCTP-EEVVNILKDIPNSGYSGEEMSD-- 539
            .:.:|..:..|...:...|.||....|    :..||:..| |..|..:.|..:...:..|:::
Yeast   550 TSYIPRDQLINYYQSLFTGYTVEEDSVRKNDLYFRQEGVPMENTVRKILDYTHKANNSREVTELE 614

  Fly   540 ----------GS----FNALKIDVFVQTLLNLGSKSFSHSFAAISKFHSVFRAL-----AETEEA 585
                      ||    ||...|.:.||.:.:.||:|.||:...|:......:.:     .:.|..
Yeast   615 SILGELKNEYGSIISDFNRFVIILLVQAVTDSGSRSLSHANKYINDLKEDLKTIFAKIELDIETK 679

  Fly   586 QICILHNIFELWSSHQQMMVVLIDKLLKLQIVDCSAVATWIFSKEMTGEFTKLYLWEILHLTIKK 650
            :..|:..:...|:::.|...::.|......::....:.|:||::  ||              :|
Yeast   680 EYIIIEAVLTFWNANPQTGFLVADAFKYAGLLTSRTIFTFIFNE--TG--------------LK- 727

  Fly   651 MNKHVIKLNTELSEAKEKLAKADSSSSDSEDDSSHKRKKPITHADKPSEEVVERMEEKLEAANVN 715
             |..:|:. |.:......|::..|..::|.::.....::..|.|:...:.:....:|.:|...||
Yeast   728 -NNGLIEA-TAIEAVFRNLSQQISEENESGNNFEFVFERLCTIANSTIDLLDVNADEDIEIPKVN 790

  Fly   716 QKRLFLIVFQRFIMILSEHLLRSDTDGRDPDTDWYRW----TIGRLQQVFLMHHEQVQKYSSTLE 776
            .:                    .|.|..:.|....:|    .||.::.:       :::||....
Yeast   791 GE--------------------MDIDDIEDDKLDLKWKYFTVIGFIKSI-------LRRYSHEYR 828

  Fly   777 TLL--FTSDLDTHI 788
            .|.  |.:::|..|
Yeast   829 ELADKFIANIDNAI 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cbp80	NP_524750.2	MIF4G	31..243	CDD:214713	52/250 (21%)
		MIF4G_like	307..473	CDD:286213	39/195 (20%)
		MIF4G_like_2	494..764	CDD:286214	53/299 (18%)
STO1	NP_013844.2	MIF4G	36..264	CDD:397130	51/242 (21%)
		MIF4G_like	346..541	CDD:370287	42/214 (20%)
		MIF4G_like_2	581..828	CDD:401145	51/292 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346141
Domainoid	1	1.000	72	1.000	Domainoid score	I2209
eggNOG	1	0.900	-	-		E1_KOG1104
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	114	1.000	Inparanoid score	I1347
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005276
OrthoInspector	1	1.000	-	-		otm46659
orthoMCL	1	0.900	-	-		OOG6_103433
Panther	1	1.100	-	-	LDO	PTHR12412
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R798
SonicParanoid	1	1.000	-	-		X3789
TreeFam	0	0.000	Not matched by this tool.
	12	11.820