Protein Alignment Cbp80 and cbc1

DIOPT Version :10

• Sequence 1: NP_524750.2
• Gene: Cbp80 / 44409
• FlyBaseID: FBgn0022942
• Length: 800
• Species: Drosophila melanogaster
• Sequence 2: NP_594104.1
• Gene: cbc1 / 2542556
• PomBaseID: SPAC6G10.07
• Length: 780
• Species: Schizosaccharomyces pombe
• Alignment Length: 802
• Identity: 180/802 - (22%)
• Similarity: 336/802 - (41%)
• Gaps: 158/802 - (19%)

  Fly     3 RRRAHDTEDEGY-DHRRNKRR----RVSE----------NQEIEDRLESLILRVGERST-----S 47
            |:|..:.|:.|: .||.|.:.    |:.:          |....|.:..:.:.:...:.     |
pombe    11 RKRTREGENYGFRPHRGNSQELLAARIKKDITFLADPRGNSVAADDINYVAMSLSREANDPETIS 75

  Fly    48 SVESNLEGLVSVLEADLGTFRLKILRILSDCAVRMP---EKCTVYTTLVGLLNAKNYKFGGEFVD 109
            ::...::....::...:......|:|    .::|:|   ||...|..|....|..::.:
pombe    76 TILDCIQTTAFIIPVKIPHLATLIIR----ASLRVPLILEKAAAYFCLQYFTNLNSFLY------ 130

  Fly   110 HMVKTFKESLKMCRWDAARYSLRFLADLVNCHVISATSLLQLLDTMIDVSNEDTVPQVRRDWFVF 174
                           ..|:..||.|  :.....:...:|..|...:.|..:::|.|.|..|.|:.
pombe   131 ---------------YEAKVDLRML--ICMSFALQPGTLKPLFSLLADAISKETKPSVWGDNFLR 178

  Fly   175 AVLSTLPW---VGRDLYEKKESALESLLLRIEVYLNKRSKK---------HHNALRVWSSDAPHP 227
            .:|..||:   ...|| .||:.|.| :|.:.|:|:..|...         |.|.
pombe   179 IILINLPYFIAANNDL-GKKDFANE-ILDQCEIYVRHRKSSITLSNPLSIHDNL----------- 230

  Fly   228 QEEYLDCLWAQIRKLRQDNWAEKHIPRPYLVFDS--ILCEALQHNLP--TIVPPPHHDNF-EYPM 287
            .||.||.|:.|:...|::::...:|.:|:..|:|  :....:..::|  |..|.|..:.. .:..
pombe   231 SEEELDLLYKQLILSRENDFTFPYISQPWKFFESDFVHIVPVSPSIPEWTFQPTPQQNELPSFKR 295

  Fly   288 PWVVYRMFDYTDCPDGPNLPGAHSIERFLIEEHLHHIIETYHHERKDCAAQLLS-----FPYK-- 345
            .:.::..|:....||..::  |.||.|.:..:.::|:    ...|.: |||:|:     |.||
pombe   296 FFELFNNFEIRTTPDASDV--AASIFRDISVDVINHL----EFNRVE-AAQVLTDLDVYFTYKTF 353

  Fly   346 -------HKIP----------LEYCIVEVVFAELFHMPTPRYLDICYGSILIELCKLQPATLPQV 393
                   :::|          .|..|||.|..||.......|..:.|.|:|||.|::.|..|...
pombe   354 ALRGTPVNELPNLDPSESRWKAEDIIVEAVLGELLGSQNTTYKPVYYHSLLIECCRIAPKILAPT 418

  Fly   394 LAQATEILFMRIDSMNTSCFDRFVNWFSYHLSNFKFTWSWDEWDSCLLLDGEHPRPKFIQEVLQK 458
            ..:...:::.....:.....|||::|||:|||||.|.|.|:||...:.||..||:..|::|.:.:
pombe   419 FGRVIRLMYTMSSDLPLQTLDRFIDWFSHHLSNFNFHWKWNEWIPDVELDDLHPKKVFMRETITR 483

  Fly   459 CLRLSYHQRITEMMPTTYAKLIPLTPV-PNYKYANEEAANLPGTTVAHQLVVAIRQKCTPEEVVN 522
            .|.|||:.||::.:|.....|:...|. ||:.|.||   ..|....:.|::.|:|.....||:..
pombe   484 ELILSYYTRISDSLPEELRCLLGEQPSGPNFVYENE---THPLYQQSSQIIEALRLHKPLEELDI 545

  Fly   523 ILKDIPNSGYSGEEMSDGSFNALKIDVFVQTLLNLGSKSFSHSFAAISKFHSVFRALA-ETEEAQ 586
            ||:        .||:.:...:|:::  .:....:|||:||||:.....|..:..:..: ::.:::
pombe   546 ILQ--------SEEIQNSETSAVRL--VMSCAYSLGSRSFSHALNVFEKHLNTLKHFSRKSLDSE 600

  Fly   587 ICILHNIFELWSSHQQMMVVLIDKLLKLQIVDCSAVATWIFSKEMTGEFTKLYLWEILHLTIKKM 651
            |.::..:|..|.......|:.:||:|...|:..:::..|:..:::| .:::.|.|.:::.|..|:
pombe   601 IEVVDELFSFWKLQPFNAVMWLDKMLNYSIISITSIIEWLIKQDVT-IWSRSYTWSLVNTTFNKL 664

  Fly   652 ---------NKHVIKLNTELSEAKE--------KLAKADSSSSDS--------------EDDSSH 685
                     ||....|..|.:|.||        .|....|.::::              |.:...
pombe   665 AARLRRSVSNKEDSSLINEANEEKEIVTNLLLSALRALISENAENIWVSHWLNLMLKYVESNFLS 729

  Fly   686 KRKKPITHADKPSEEVVERMEE 707
            .:|..|..|::|.:|.....:|
pombe   730 VKKDTIEEANEPVQENTSEEQE 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cbp80	NP_524750.2	MIF4G	31..243	CDD:214713	44/231 (19%)
		MIF4G_like	307..473	CDD:370287	58/189 (31%)
		MIF4G_like_2	488..770	CDD:462675	52/252 (21%)
cbc1	NP_594104.1	MIF4G	36..249	CDD:397130	47/252 (19%)
		MIF4G_like	309..499	CDD:370287	60/196 (31%)
		MIF4G_like_2	514..751	CDD:462675	51/250 (20%)