Protein Alignment MSI1 and Hrb98DE

DIOPT Version :10

• Sequence 1: NP_002433.1
• Gene: MSI1 / 4440
• HGNCID: 7330
• Length: 362
• Species: Homo sapiens
• Sequence 2: NP_524543.1
• Gene: Hrb98DE / 43385
• FlyBaseID: FBgn0001215
• Length: 365
• Species: Drosophila melanogaster
• Alignment Length: 200
• Identity: 76/200 - (38%)
• Similarity: 117/200 - (58%)
• Gaps: 6/200 - (3%)

Human     2 ETDAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFV 66
            :.|.||..:..|:...   |:|||||.::||.|.|:.:|.::|.:.:.:||:||.|||||||||:
  Fly    16 DDDFPQDSITEPEHMR---KLFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDPRTKRSRGFGFI 77

Human    67 TFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRR--AQPKMVTRTKKIFVGGLSVNTTVEDVKQYF 129
            |:...:.:|:......|::|.:.::||.|.||:  ..|......||:|||.|..:...:.::.||
  Fly    78 TYSHSSMIDEAQKSRPHKIDGRVVEPKRAVPRQDIDSPNAGATVKKLFVGALKDDHDEQSIRDYF 142

Human   130 EQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTG 194
            :.||.:.|..::.||.|.:.|||.||.|:..|.|:||.....|::|.|||:.|||.||: ....|
  Fly   143 QHFGNIVDINIVIDKETGKKRGFAFVEFDDYDPVDKVVLQKQHQLNGKMVDVKKALPKQ-NDQQG 206

Human   195 SARGR 199
            ...||
  Fly   207 GGGGR 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MSI1	NP_002433.1	RRM1_MSI	21..96	CDD:409990	31/74 (42%)
		PABP-1234	<32..339	CDD:130689	64/169 (38%)
		RRM2_MSI	110..183	CDD:240769	28/72 (39%)
Hrb98DE	NP_524543.1	RRM1_hnRNPA_like	32..109	CDD:409992	32/76 (42%)
		RRM_SF	123..195	CDD:473069	28/71 (39%)