DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpp30 and RPP1

DIOPT Version :9

Sequence 1:	NP_001259808.1	Gene:	Rpp30 / 44392	FlyBaseID:	FBgn0283652	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_011929.1	Gene:	RPP1 / 856459	SGDID:	S000001104	Length:	293	Species:	Saccharomyces cerevisiae

Alignment Length:	301	Identity:	75/301 - (24%)
Similarity:	130/301 - (43%)	Gaps:	26/301 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DFSIPYNKD---DSVLRALLNELVET-------GYKTVAIDQSFDHSKKDPGKRGSEMFPEPHKI 63
            |.::|:.::   |.|....:|.|::|       ||..:||:.:.:||:|.|   .......|..|
Yeast     4 DLNVPWPQNSYADKVTSQAVNNLIKTLSTLHMLGYTHIAINFTVNHSEKFP---NDVKLLNPIDI 65

  Fly    64 EHLRKEFQDK--LRILQRITILYVDVNVAHAMSVSHNLRKFNLIAGQPKTDAALTHCCTAFNGDL 126
            :....|..|:  |::..|||::..|  .:...|:|...:.|:::|..|.::..||...|..:.||
Yeast    66 KRRFGELMDRTGLKLYSRITLIIDD--PSKGQSLSKISQAFDIVAALPISEKGLTLSTTNLDIDL 128

  Fly   127 ITFDPVAGSRL--LVNRKAYQVAVRRGMFFEIKYAPSICDSNNRKDMIKIAQNYCTKGKSKNVIF 189
            :||.  .||||  .:..|:....|.||:..||.|..::.|...|:..:...::.....:|:.::.
Yeast   129 LTFQ--YGSRLPTFLKHKSICSCVNRGVKLEIVYGYALRDVQARRQFVSNVRSVIRSSRSRGIVI 191

  Fly   190 SSGAAHEFQLRGPYDVANLAFIFGLSEDQGKNAVDGHCRELFLKAEARRLGKTIMFLKGNGPIIY 254
            .|||....:.|....|.:|....||..|:...|:......:.|....|........:.|.|....
Yeast   192 GSGAMSPLECRNILGVTSLIKNLGLPSDRCSKAMGDLASLVLLNGRLRNKSHKQTIVTGGGSGNG 256

  Fly   255 SDSSEDEKSTEDEMKGLKPQIGKADAFEVKDGTEHAIKRLK 295
            .|...|.:.. |:::.:|......||.::    .||.||.|
Yeast   257 DDVVNDVQGI-DDVQTIKVVKRSMDAEQL----GHASKRHK 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpp30	NP_001259808.1	RNase_P_p30	8..226	CDD:280117	60/230 (26%)
RPP1	NP_011929.1	RNase_P_p30	3..227	CDD:396447	60/229 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346229
Domainoid	1	1.000	69	1.000	Domainoid score	I2310
eggNOG	1	0.900	-	-		E1_COG1603
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38180
Inparanoid	1	1.050	72	1.000	Inparanoid score	I1686
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54344
OrthoFinder	1	1.000	-	-		FOG0004460
OrthoInspector	1	1.000	-	-		oto100005
orthoMCL	1	0.900	-	-		OOG6_102854
Panther	1	1.100	-	-	LDO	PTHR13031
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1168
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790