DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CIII and Mdga1

DIOPT Version :9

Sequence 1:	NP_524747.1	Gene:	Sr-CIII / 44382	FlyBaseID:	FBgn0020376	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001355352.1	Gene:	Mdga1 / 74762	MGIID:	1922012	Length:	956	Species:	Mus musculus

Alignment Length:	194	Identity:	48/194 - (24%)
Similarity:	80/194 - (41%)	Gaps:	41/194 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 SVGDHSCDFEREDMCGWRASKAIPQPWKRISAAADFLKEKCLQQDHT-----FQSDVEGHFIRLQ 196
            |:.|::|.||.|.:||:.........|.|.:|    |.:...:..:|     .....||:::.::
Mouse   748 SLSDNTCHFEDEKICGYTQDLTDNFDWTRQNA----LTQNPKRSPNTGPPTDISGTPEGYYMFIE 808

  Fly   197 SQVHASR------TYHFISPIYPRNLTVGHSLWF---QFELFMFGSEVRNLTISVKPSSMAVED- 251
            :    ||      ....:||:|      ..|..|   .|...|:|..:.:|.:.|:..:....|
Mouse   809 T----SRPRELGDRARLVSPLY------NASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGTLDT 863

  Fly   252 -MWNSFRNICTKLTVSGDQGPNWKSQSISIDEMESDFQVVFTVVDPSSLHGDIGIDDVKFIKSE 314
             .|          ::||::|..|:...:.|:. ...||::|..|..|...|||.||||...|.|
Mouse   864 HAW----------SLSGNKGNVWQQAHVPINP-SGPFQIIFEGVRGSGYLGDIAIDDVTLKKGE 916

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CIII	NP_524747.1	CCP	27..>62	CDD:153056
		MAM	143..310	CDD:279023	44/182 (24%)
		MAM	143..310	CDD:99706	44/182 (24%)
Mdga1	NP_001355352.1	Ig	56..115	CDD:353325
		IG	152..217	CDD:214652
		IG	248..326	CDD:214652
		I-set	333..418	CDD:336764
		IG	450..535	CDD:214652
		Ig_3	538..620	CDD:339005
		MAM	754..918	CDD:334181	46/188 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	780..799		2/18 (11%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9081
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910