DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CIII and si:ch211-106h4.4

DIOPT Version :9

Sequence 1:	NP_524747.1	Gene:	Sr-CIII / 44382	FlyBaseID:	FBgn0020376	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	XP_017207311.2	Gene:	si:ch211-106h4.4 / 559790	ZFINID:	ZDB-GENE-070705-14	Length:	2402	Species:	Danio rerio

Alignment Length:	338	Identity:	71/338 - (21%)
Similarity:	126/338 - (37%)	Gaps:	98/338 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 YMVIQSIASCEPDILLRNGKVTELSSWLLGDSIKFECNPGFSLQGKT---WHLGNGNMMKRYCAK 79
            :|.|.|:.|.:|.      :...|.|              |..|.|.   |:|..|..:
Zfish   268 FMYIGSLRSSKPP------QTARLIS--------------FPQQAKCVSFWYLMYGGRI------ 306

  Fly    80 AGCNDIEKQANG--TIL---TATDGLK--------AEIECDDEFVLSGNSFTYCNGTKWIIKLGT 131
            .....:.|..||  |::   |...|.|        |:.:...:|:..|...|    ::..|.:..
Zfish   307 GSLKFLIKHTNGEQTLMWMRTGNQGNKWRFVDLSFADSKEPIQFIFEGILET----SEGYIAIDD 367

  Fly   132 CQLANSVGDHSCDFERE-----DMCGWRASKAIPQPWKRISAAADFLKEKCLQQDHTFQSDVEGH 191
            .|::.|: :.||..|||     .:||..:.......|.|...... :.......|||.::| :|.
Zfish   368 VQVSGSI-NGSCPAERECTFQGSLCGLSSDLTTDFTWIRTKGELS-IGTPSPATDHTLETD-KGF 429

  Fly   192 FI-------------RLQSQVHASRTYHFISPIYPRNLTVGHSLWFQFELFMFGSEVRNLTISVK 243
            ::             |:.::|::..:.|            |..|.|.::  |.|.:|.:|.|.|:
Zfish   430 YLSAQLWKNPSGSRGRMMTEVNSPTSEH------------GECLMFWYQ--MNGKDVGSLNIYVQ 480

  Fly   244 ---PSSMAVEDMWNSFRNICTKLTVSGDQGPNWKSQSISIDEMESDFQVVFTVVDPSSLHGDIGI 305
               .|.::...:|          :|:||||..|:....::....|.::::|..|..:....||.|
Zfish   481 DVLSSKISQISVW----------SVNGDQGQKWRHGRATVRSPHSSYKIIFEAVVGNEREHDIAI 535

  Fly   306 DDVKFIKSETNEP 318
            ||:..:    |:|
Zfish   536 DDLTIL----NDP 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CIII	NP_524747.1	CCP	27..>62	CDD:153056	4/34 (12%)
		MAM	143..310	CDD:279023	41/187 (22%)
		MAM	143..310	CDD:99706	41/187 (22%)
si:ch211-106h4.4	XP_017207311.2	LDLa	18..53	CDD:238060
		MAM	56..210	CDD:332481
		MAM	223..378	CDD:99706	27/140 (19%)
		MAM	384..545	CDD:99706	39/191 (20%)
		MAM	551..708	CDD:99706
		MAM	732..888	CDD:99706
		MAM	894..1045	CDD:306977
		MAM	1050..1199	CDD:99706
		MAM	1212..1365	CDD:99706
		LDLa	1375..1409	CDD:238060
		MAM	1418..1571	CDD:332481
		LDLa	1609..1646	CDD:238060
		MAM	1645..1804	CDD:332481
		MAM	1818..1974	CDD:99706
		MAM	1981..2138	CDD:99706
		MAM	2144..2306	CDD:99706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9895
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006092
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.000