DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CIII and mdga2a

DIOPT Version :9

Sequence 1:	NP_524747.1	Gene:	Sr-CIII / 44382	FlyBaseID:	FBgn0020376	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	XP_021328869.1	Gene:	mdga2a / 368826	ZFINID:	ZDB-GENE-030616-360	Length:	964	Species:	Danio rerio

Alignment Length:	302	Identity:	71/302 - (23%)
Similarity:	111/302 - (36%)	Gaps:	63/302 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 GFSLQGKTWHLGNGNMMKRYCA-KAGCNDIEKQANGTILTATDGLKAEIECDDEF----VLSGN- 115
            ||.||   |...|.|.:.|..| :.|...:..|.         ..:.||..:|..    :||.|
Zfish   653 GFKLQ---WTQMNPNAVDRIMAYRLGIKQMGHQR---------WWEQEIPTEDNIQKGELLSYNL 705

  Fly   116 -----------------SFTYCNGTKWIIKLGTCQLANS-VGDH----SCDFEREDMCGWRASKA 158
                             .|...:.|:.||:........: |..|    .|.||.:.:|.:...|.
Zfish   706 TELIKPEAYQVRLTPITRFGEGDSTERIIRYSEASRDTAPVNPHWSKFHCGFEEDTICMFTQDKT 770

  Fly   159 IPQPWKRISAA---ADFLKEKCLQQDHT-----FQSDVEGHFIRLQSQVHASRTYHF-ISPIYP- 213
            ....|.|.|||   ..:........|.:     |...:|....||:.......|..| ::|..|
Zfish   771 EEFDWTRHSAATRDTKYTPNTGPSSDRSGSKQGFYMYIETSRPRLEGDKARLLTPSFNVAPKNPY 835

  Fly   214 RNLTVGHSLWFQFELFMFGSEVRNLTISVKPSSMAVED--MWNSFRNICTKLTVSGDQGPNWKSQ 276
            .|:....:..|.|...|:|..:..|.:.::..|...:|  :|          |:||:||..|:..
Zfish   836 GNVASNPTYCFSFYYHMYGKHIGTLNVYLRQKSQTGQDTSVW----------TLSGNQGDRWRQA 890

  Fly   277 SISIDEMESDFQVVFTVVDPSSLHGDIGIDDVKFIKSETNEP 318
            .::|:. .|.||:|...:..|.:.|||.:|||...:.|..:|
Zfish   891 RVNINP-TSSFQIVMEGIRGSGIEGDIAVDDVTIEEGECRDP 931

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CIII	NP_524747.1	CCP	27..>62	CDD:153056	3/4 (75%)
		MAM	143..310	CDD:279023	46/178 (26%)
		MAM	143..310	CDD:99706	46/178 (26%)
mdga2a	XP_021328869.1	Ig_3	50..114	CDD:316449
		IG	154..223	CDD:214652
		IGc2	257..318	CDD:197706
		I-set	350..421	CDD:333254
		Ig_3	442..517	CDD:316449
		MAM	755..929	CDD:306977	47/184 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9895
eggNOG	1	0.900	-	-		E1_2CMY0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900