DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CIII and Mep1b

DIOPT Version :9

Sequence 1:	NP_524747.1	Gene:	Sr-CIII / 44382	FlyBaseID:	FBgn0020376	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_037315.1	Gene:	Mep1b / 25727	RGDID:	3081	Length:	704	Species:	Rattus norvegicus

Alignment Length:	215	Identity:	54/215 - (25%)
Similarity:	84/215 - (39%)	Gaps:	59/215 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 KLGTCQLANSVGDHSCDFEREDMCGWRASKAIPQPWKRISAAADFLKEKCLQQDHT--FQSDVEG 190
            :|.:|..:.|..| |||||.|::||...|......|:|:|...     ...:.||:  .|....|
  Rat   252 QLYSCTSSLSFMD-SCDFELENICGMIQSSQDSADWQRLSQVL-----SGPENDHSNMGQCKDSG 310

  Fly   191 HFIR-------------LQSQVHASRTYHFISPIYPRNLTVGHSLWFQ---FELFMFGSEVRNLT 239
            .|:.             |:|:|           :||:.       .||   |.|:..||....|.
  Rat   311 FFMHFNTSTGNGGITAMLESRV-----------LYPKR-------GFQCVEFYLYNSGSGNGQLN 357

  Fly   240 ISVKPSSMAVED----MWNSFRNICTKLTVSGDQGPNWKSQSISIDEMESDFQVVFT-VVDPSSL 299
            :..:..:...:|    :....|:|.|         .:|:...:::...|. |:|||. |..|.:.
  Rat   358 VYTREYTAGHQDGVLTLQREIRDIPT---------GSWQLYYVTLQVTEK-FRVVFEGVGGPGAS 412

  Fly   300 HGDIGIDDVKFIKSETNEPH 319
            .|.:.|||:..  |||..||
  Rat   413 SGGLSIDDINL--SETRCPH 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CIII	NP_524747.1	CCP	27..>62	CDD:153056
		MAM	143..310	CDD:279023	44/189 (23%)
		MAM	143..310	CDD:99706	44/189 (23%)
Mep1b	NP_037315.1	ZnMc	30..256	CDD:294052	1/3 (33%)
		Astacin	70..258	CDD:279708	2/5 (40%)
		MAM	266..430	CDD:279023	47/198 (24%)
		MAM	266..428	CDD:99706	47/196 (24%)
		MATH	428..586	CDD:295307	2/3 (67%)
		EGF_CA	609..647	CDD:238011
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000