Protein Alignment Rab18 and RAB2B

DIOPT Version :10

• Sequence 1: NP_524744.2
• Gene: Rab18 / 44360
• FlyBaseID: FBgn0015794
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_116235.2
• Gene: RAB2B / 84932
• HGNCID: 20246
• Length: 216
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 80/191 - (41%)
• Similarity: 122/191 - (63%)
• Gaps: 8/191 - (4%)

  Fly     7 KLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERFRSLT 71
            |.::||::|||||.|:.:|.:.:|...||:|||::|.::::.:||...|:.:|||||.|.|||:|
Human     8 KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSIT 72

  Fly    72 PSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNKIDEE--RVVDREEGRK 134
            .|:||.|.||:||||||.|::...|.:||.:...:|.: |:.|:::|||.|.|  |.|.||||..
Human    73 RSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSS-NMVIMLIGNKSDLESRRDVKREEGEA 136

  Fly   135 FARKHRALFIETSAKCDQFVSDVF----KDVVEKIVSSEYFNNGNASAGLDIASDRDLEAS 191
            |||:|..:|:|||||....|.:.|    |::..|| ....|:..|.:.|:.|...:.:..|
Human   137 FAREHGLIFMETSAKTACNVEEAFINTAKEIYRKI-QQGLFDVHNEANGIKIGPQQSISTS 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	73/163 (45%)
RAB2B	NP_116235.2	PLN03108	1..216	CDD:178655	80/191 (42%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		6/8 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..216		1/8 (13%)