Protein Alignment Rab18 and Rab1b

DIOPT Version :10

• Sequence 1: NP_524744.2
• Gene: Rab18 / 44360
• FlyBaseID: FBgn0015794
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_083852.1
• Gene: Rab1b / 76308
• MGIID: 1923558
• Length: 201
• Species: Mus musculus
• Alignment Length: 199
• Identity: 80/199 - (40%)
• Similarity: 119/199 - (59%)
• Gaps: 9/199 - (4%)

  Fly     3 DRAIKLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERF 67
            |...|||:||:||||||.|:.||.::.:.:::..|||:|||.:.:::||...|:.:|||||.|||
Mouse     6 DYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERF 70

  Fly    68 RSLTPSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNKID--EERVVDRE 130
            |::|.|:||.|.|.|:|||:|.::|...::.||.|:|.|: :.|:..::||||.|  .::|||..
Mouse    71 RTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYA-SENVNKLLVGNKSDLTTKKVVDNT 134

  Fly   131 EGRKFARKHRALFIETSAKCDQFVSDVFKDVVEKIVSSEYFNNGNASAG----LDIASDRDLEAS 191
            ..::||......|:|||||....|...|..:..:|  .:....|.||.|    |.|.|.....||
Mouse   135 TAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEI--KKRMGPGAASGGERPNLKIDSTPVKPAS 197

  Fly   192 ASTC 195
            ...|
Mouse   198 GGCC 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	68/160 (43%)
Rab1b	NP_083852.1	Rab1_Ypt1	7..172	CDD:206661	69/167 (41%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q9H0U4	30..45		3/14 (21%)
		Switch 2 region, required for interaction with REP1/CHM. /evidence=ECO:0000250|UniProtKB:Q9H0U4	64..83		12/18 (67%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q9H0U4	65..80		9/14 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..201		9/26 (35%)