Protein Alignment Rab18 and RAB8B

DIOPT Version :10

• Sequence 1: NP_524744.2
• Gene: Rab18 / 44360
• FlyBaseID: FBgn0015794
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_057614.1
• Gene: RAB8B / 51762
• HGNCID: 30273
• Length: 207
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 76/202 - (37%)
• Similarity: 124/202 - (61%)
• Gaps: 12/202 - (5%)

  Fly     3 DRAIKLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERF 67
            |...|||:||:|||||:.|:.||.|:.|:.....|||:|||.:.:::||...|:.:|||||.|||
Human     6 DYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERF 70

  Fly    68 RSLTPSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNKID--EERVVDRE 130
            |::|.::||.|:|.:||||||:..|...::.|:..::.::.: ::..:::|||.|  ::|.|.:|
Human    71 RTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASS-DVERMILGNKCDMNDKRQVSKE 134

  Fly   131 EGRKFARKHRALFIETSAKCDQFVSDVF----KDVVEKIVSSEYFNNGN-ASAG--LDIASDRDL 188
            .|.|.|..:...|:|||||....|.:.|    :|::.|:  :...|:.| |.||  :.|..:|..
Human   135 RGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKL--NRKMNDSNSAGAGGPVKITENRSK 197

  Fly   189 EASASTC 195
            :.|...|
Human   198 KTSFFRC 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	65/164 (40%)
RAB8B	NP_057614.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	66/166 (40%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		10/16 (63%)