DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab18 and rab18b

DIOPT Version :9

Sequence 1:	NP_524744.2	Gene:	Rab18 / 44360	FlyBaseID:	FBgn0015794	Length:	197	Species:	Drosophila melanogaster
Sequence 2:	NP_001003449.1	Gene:	rab18b / 445055	ZFINID:	ZDB-GENE-040801-185	Length:	205	Species:	Danio rerio

Alignment Length:	194	Identity:	96/194 - (49%)
Similarity:	131/194 - (67%)	Gaps:	2/194 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IKLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERFRSL 70
            :|:|:|||||||||||:.||.::.||.....|||:|||.|.:.:||...|:|:|||||.||||:|
Zfish     9 LKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTIAIDGNRAKLAIWDTAGQERFRTL 73

  Fly    71 TPSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNKIDEE-RVVDREEGRK 134
            |||:||.|.|.|||||:|.||:..|||.||.||::|....::..::||||||:: |.|||.||.|
Zfish    74 TPSYYRGAQGVILVYDVTKRDTFTKLENWLNELETYCTRNDLVKMLVGNKIDKDNREVDRNEGLK 138

  Fly   135 FARKHRALFIETSAKCDQFVSDVFKDVVEKIVSSE-YFNNGNASAGLDIASDRDLEASASTCYC 197
            |||||..||||.|||....|...|:::||||:.:. .:.:...:.|:.::.:......|...||
Zfish   139 FARKHSMLFIEASAKTRDGVQCAFEELVEKILQTPGLWESSIQNHGVQLSDNEPQRQGACGGYC 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab18	NP_524744.2	RAB	6..166	CDD:197555	91/160 (57%)
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	90/159 (57%)
rab18b	NP_001003449.1	RAB	9..172	CDD:197555	92/162 (57%)
		Rab18	9..169	CDD:206656	90/159 (57%)
		Effector region. /evidence=ECO:0000250	37..45		3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	182	1.000	Domainoid score	I3395
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40765
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3930
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247169at2759
OrthoFinder	1	1.000	-	-		FOG0004111
OrthoInspector	1	1.000	-	-		otm26178
orthoMCL	1	0.900	-	-		OOG6_101993
Panther	1	1.100	-	-	LDO	PTHR24073
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2740
SonicParanoid	1	1.000	-	-		X2853
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	13.000