DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab18 and RabX1

DIOPT Version :9

Sequence 1:	NP_524744.2	Gene:	Rab18 / 44360	FlyBaseID:	FBgn0015794	Length:	197	Species:	Drosophila melanogaster
Sequence 2:	NP_524713.1	Gene:	RabX1 / 44172	FlyBaseID:	FBgn0015372	Length:	261	Species:	Drosophila melanogaster

Alignment Length:	164	Identity:	60/164 - (36%)
Similarity:	97/164 - (59%)	Gaps:	5/164 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KLLVIGESGVGKSSLIRRFVENKFDQNHD--VTIGMDFKSKVMQVDGIDYKVALWDTAGAERFRS 69
            |:||:|..||||:.|:.|:::|...:...  .||.:.|.:..:.:|.:..|:.:|||||.||:|:
  Fly     7 KVLVLGSRGVGKTRLVIRYIKNTLHRKESEVPTIAVSFFTCNIILDEVKIKLQIWDTAGQERYRA 71

  Fly    70 LTPSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNKID--EERVVDREEG 132
            :.|.:||.|..||||:|:|...:..::::|:.||.....:|.| :.:||||:|  .:|.|.|||.
  Fly    72 VAPMYYRNANAAILVFDLTQYKTFTEIKSWIQELHRNVQDPMI-LTLVGNKMDMQAQRAVSREEA 135

  Fly   133 RKFARKHRALFIETSAKCDQFVSDVFKDVVEKIV 166
            ..||....|.:.|||.:.||.:..||....:.:|
  Fly   136 FVFATSIGATYFETSTETDQGLEQVFISTAQGLV 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab18	NP_524744.2	RAB	6..166	CDD:197555	59/162 (36%)
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	59/161 (37%)
RabX1	NP_524713.1	Ras	7..166	CDD:278499	59/159 (37%)
RabX1	NP_524713.1	Rab	7..166	CDD:206640	59/159 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454449
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24073
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030