Protein Alignment Rab18 and RAB15

DIOPT Version :10

• Sequence 1: NP_524744.2
• Gene: Rab18 / 44360
• FlyBaseID: FBgn0015794
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_001295083.1
• Gene: RAB15 / 376267
• HGNCID: 20150
• Length: 212
• Species: Homo sapiens
• Alignment Length: 208
• Identity: 78/208 - (37%)
• Similarity: 125/208 - (60%)
• Gaps: 14/208 - (6%)

  Fly     3 DRAIKLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERF 67
            |...:||:||:|||||:.|:.||.:|:|..:|..|||:|||.|.::||||..::.:|||||.||:
Human     6 DVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQERY 70

  Fly    68 RSLTPSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNKIDEE--RVVDRE 130
            :::|..:||:|.|..|||||:|..|...:..|::::|.|:.. .:..|::|||.|||  |.|.||
Human    71 QTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPE-GVQKILIGNKADEEQKRQVGRE 134

  Fly   131 EGRKFARKHRALFIETSAKCDQFVSDVFKDVVEKIVSSEYFN----NGNASAGLDIASDRDLEA- 190
            :|::.|:::...|.||||..:..:.:.|..:.|.::.:....    ...||..|.:|...:.|.
Human   135 QGQQLAKEYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELEGLRMRASNELALAELEEEEGK 199

  Fly   191 ------SASTCYC 197
                  |:.||:|
Human   200 PEGPANSSKTCWC 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	68/160 (43%)
RAB15	NP_001295083.1	Rab15	9..172	CDD:206698	68/163 (42%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		6/13 (46%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		8/16 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..212		4/18 (22%)