Protein Alignment Rab18 and RAB7B

DIOPT Version :10

• Sequence 1: NP_524744.2
• Gene: Rab18 / 44360
• FlyBaseID: FBgn0015794
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_796377.3
• Gene: RAB7B / 338382
• HGNCID: 30513
• Length: 199
• Species: Homo sapiens
• Alignment Length: 171
• Identity: 56/171 - (32%)
• Similarity: 96/171 - (56%)
• Gaps: 15/171 - (8%)

  Fly     6 IKLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERFRSL 70
            :||:::|..||||:||:.::|...|.:.:..|:|....||::.:.....|:.:|||.|.|||||:
Human     9 LKLIIVGAIGVGKTSLLHQYVHKTFYEEYQTTLGASILSKIIILGDTTLKLQIWDTGGQERFRSM 73

  Fly    71 TPSFYRKALGAILVYDITSRDSLVKLETW----LAEL----DSYSDNPNIAIIVVGNKID-EERV 126
            ..:||:.:.|.||.:|:|..:|...|:.|    ||::    .||      .::::||||| .:|.
Human    74 VSTFYKGSDGCILAFDVTDLESFEALDIWRGDVLAKIVPMEQSY------PMVLLGNKIDLADRK 132

  Fly   127 VDREEGRKFARKHRALFIETSAKCDQFVSDVFKDVVEKIVS 167
            |.:|..:.:.|:....:.|.|||.|..|...|:.:..:.:|
Human   133 VPQEVAQGWCREKDIPYFEVSAKNDINVVQAFEMLASRALS 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	55/167 (33%)
RAB7B	NP_796377.3	Rab	9..169	CDD:206640	55/165 (33%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P51149	28..41		2/12 (17%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P51149	67..82		7/14 (50%)