Protein Alignment Rab18 and RAB12

DIOPT Version :10

• Sequence 1: NP_524744.2
• Gene: Rab18 / 44360
• FlyBaseID: FBgn0015794
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_001020471.3
• Gene: RAB12 / 201475
• HGNCID: 31332
• Length: 340
• Species: Homo sapiens
• Alignment Length: 168
• Identity: 65/168 - (38%)
• Similarity: 111/168 - (66%)
• Gaps: 4/168 - (2%)

  Fly     2 ADRAIKLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAER 66
            ||..:::::||..||||:||:.||.::.|.:....|:|:|||.|.:::.|...::.:|||||.||
Human   135 ADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQER 199

  Fly    67 FRSLTPSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNKID--EERVVDR 129
            |.|:|.::||.|.|.|||||||.:::...|..|:..:|.|: :.:..:::||||:|  .:|.:.|
Human   200 FNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYA-SEDAELLLVGNKLDCETDREITR 263

  Fly   130 EEGRKFARKHRAL-FIETSAKCDQFVSDVFKDVVEKIV 166
            ::|.|||::...: |.|.|||.:..|.::|..:|:.|:
Human   264 QQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDIL 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	62/161 (39%)
RAB12	NP_001020471.3	Rab12	139..340	CDD:206699	63/164 (38%)