Protein Alignment Rab18 and Rab5b

DIOPT Version :10

• Sequence 1: NP_524744.2
• Gene: Rab18 / 44360
• FlyBaseID: FBgn0015794
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_803130.1
• Gene: Rab5b / 19344
• MGIID: 105938
• Length: 215
• Species: Mus musculus
• Alignment Length: 181
• Identity: 76/181 - (41%)
• Similarity: 117/181 - (64%)
• Gaps: 6/181 - (3%)

  Fly     7 KLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERFRSLT 71
            ||:::|||.||||||:.|||:.:|.:..:.|||..|.::.:.:|....|..:|||||.||:.||.
Mouse    22 KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLA 86

  Fly    72 PSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNKID--EERVVDREEGRK 134
            |.:||.|..||:|||||::::..:.:||:.||...: :|:|.|.:.|||.|  .:|:|:.||.:.
Mouse    87 PMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQA-SPSIVIALAGNKADLANKRMVEYEEAQA 150

  Fly   135 FARKHRALFIETSAKCDQFVSDVFKDVVEKIVSSEYFNNGNA---SAGLDI 182
            :|..:..||:|||||....|:|:|..:.:|:..||..|.|.|   |.|:|:
Mouse   151 YADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRGVDL 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	67/159 (42%)
Rab5b	NP_803130.1	Rab5_related	20..182	CDD:206653	68/160 (43%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	44..56		4/11 (36%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	77..93		9/15 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..215		6/16 (38%)