Protein Alignment Rab18 and RAB39B

DIOPT Version :10

• Sequence 1: NP_524744.2
• Gene: Rab18 / 44360
• FlyBaseID: FBgn0015794
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_741995.1
• Gene: RAB39B / 116442
• HGNCID: 16499
• Length: 213
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 74/211 - (35%)
• Similarity: 118/211 - (55%)
• Gaps: 27/211 - (12%)

  Fly     7 KLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVD-GIDYKVALWDTAGAERFRSL 70
            :|:|||:|.||||.|||||.|.:|.|..|.|:|:||.|:::::: |...|:.:|||||.|||||:
Human    10 RLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQERFRSI 74

  Fly    71 TPSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNK--IDEERVVDREEGR 133
            |.::||.::|.:|::|||:|.|...:..||.|...:.....|..::||:|  :|.:|.|.|.|..
Human    75 TRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRHEAE 139

  Fly   134 KFARKHRALFIETSAK----CDQFVSDVFKDVVEKI-------------VSSEYFNNGNASAGLD 181
            |.|..:...:|||||:    .::..:|:.:|:.|.:             |.|.:..|       .
Human   140 KLAAAYGMKYIETSARDAINVEKAFTDLTRDIYELVKRGEITIQEGWEGVKSGFVPN-------V 197

  Fly   182 IASDRDLEASASTCYC 197
            :.|..::..|...|.|
Human   198 VHSSEEVVKSERRCLC 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	67/164 (41%)
RAB39B	NP_741995.1	Rab39	7..213	CDD:133311	73/209 (35%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	35..43		3/7 (43%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		9/15 (60%)