Protein Alignment Rab18 and RAB10

DIOPT Version :10

• Sequence 1: NP_524744.2
• Gene: Rab18 / 44360
• FlyBaseID: FBgn0015794
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_057215.3
• Gene: RAB10 / 10890
• HGNCID: 9759
• Length: 200
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 75/195 - (38%)
• Similarity: 118/195 - (60%)
• Gaps: 4/195 - (2%)

  Fly     3 DRAIKLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERF 67
            |...|||:||:|||||:.::.||.::.|:.....|||:|||.|.:::.|...|:.:|||||.|||
Human     7 DLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERF 71

  Fly    68 RSLTPSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNK--IDEERVVDRE 130
            .::|.|:||.|:|.:||||||:..|...:..||..:|.:: |.::..:::|||  :|::|||.:.
Human    72 HTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHA-NEDVERMLLGNKCDMDDKRVVPKG 135

  Fly   131 EGRKFARKHRALFIETSAKCDQFVSDVFKDVVEKIVSSEYFNNGNASAGLDIASDRDLEASASTC 195
            :|.:.||:|...|.|||||.:..:...|..:.|.|:........| |..:||:|...:....|.|
Human   136 KGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPN-SENVDISSGGGVTGWKSKC 199

  Fly   196  195
            Human   200  199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	66/160 (41%)
RAB10	NP_057215.3	Rab8_Rab10_Rab13_like	7..173	CDD:206659	68/166 (41%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	32..46		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	64..81		10/16 (63%)