Protein Alignment CG46339 and Rnpep

DIOPT Version :9

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_112359.2
• Gene: Rnpep / 81761
• RGDID: 621137
• Length: 650
• Species: Rattus norvegicus
• Alignment Length: 663
• Identity: 144/663 - (21%)
• Similarity: 236/663 - (35%)
• Gaps: 185/663 - (27%)

  Fly   295 RPLHYSLLIEPSVATSIS---------------------------NGSLTIEIERDVSKVTSWEP 332
            ||||.:..::.:.|:|..                           ||..|:|:...:.:..|  .
  Rat    15 RPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLNGKATLELRCLLPEGAS--E 77

  Fly   333 IVLDVHN-VSISNVRVIRALADGASNASEEQDLDFD--SDYGEDNATFVINLSKTLAVETQLRVL 394
            :.||.|: :.:....::|.........:|.......  |.||:  |..|:......|.|   |..
  Rat    78 LRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQ--ALCVVFPKPCCAAE---RFR 137

  Fly   395 LSLDFVSQVTDTLQGIYKTSYTNPDTKNEEWM------------ISTQFSPVDARRAFPCFDRPD 447
            |.|                :|...:.....|:            :.||...|..|..|||||.|.
  Rat   138 LEL----------------TYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPA 186

  Fly   448 MKANFSISIVRPMQFKMALSNMPKSGSRRFRRGFIRDDFETTPKMPTYLVAFIVSNMVDSRLASQ 512
            :|..:|..:..|..|...:     |.|...|||..:..|:....:|:||:|..:.:     |||.
  Rat   187 VKCTYSALVEVPDGFTAVM-----SASTWERRGPNKFFFQMNQPIPSYLIALAIGD-----LASA 241

  Fly   513 DSGLTPRVEIWTRPQFVGMTHYAYK-MVRKFLPYYEDFFGIKNKLP----KIDLVSV-PDFGFAA 571
            :.|  ||..:|..|..:......|. ::.:||...|..||     |    :.||:.: |.|.|..
  Rat   242 EVG--PRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFG-----PYVWGRYDLLFMPPSFPFGG 299

  Fly   572 MENWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHELAHQWFGNLVTPKWWDDLWLKEGFAC 636
            ||| ..:||....||..:           :.:|.:|.||::|.|||||||...|.:.||.|||..
  Rat   300 MEN-PCLTFVTPCLLAGD-----------RSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTM 352

  Fly   637 Y-----------MSYKALEHAHPEF---QSMDT------LTMLEFKESMEHDADNTSHAISFDVR 681
            |           .:|..||.|....   |.||.      |..|..|.....|.|:|
  Rat   353 YAQRRISTILFGAAYTCLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDT--------- 408

  Fly   682 STNDVRRIFDPISYSKGTILLRMLNSIVGD-VAFRSATRDLLKKFAYGNMDRDDLWAMLTRHGHE 745
                    ::...|.||...:..|..:||| ..|....:..:.:|.:.::..:|.......:..|
  Rat   409 --------YNETPYEKGYCFVSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPE 465

  Fly   746 QGTLPKDLSVKQI----MDSWITQPGYPVVNVERRGADLVLRQERYLLPSKNTADQ--------- 797
            .    |...|..|    .:.|:..||:|....:....|.:::      |::..|:.
  Rat   466 L----KKKGVDSIPGFEFNRWLNTPGWPPYLPDLSPGDSLMK------PAEELAELWAASEPDMQ 520

  Fly   798 -------STW-FIPITFETDELRKGDNIPTHWMRSEDEEELIVGNVFAHSSNSDN---------V 845
                   ||| ...:.:..|::.:...:|...::.       :|..:...||:.|         :
  Rat   521 AIEAVAISTWKTYQLVYFLDKILQKSPLPPGNVKK-------LGETYPKISNAQNAELRLRWGQI 578

  Fly   846 IYLNLNRQGYYRV 858
            |..|.:::.:::|
  Rat   579 ILKNDHQEEFWKV 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	Peptidase_M1	296..698	CDD:279741	111/469 (24%)
		M1_APN_2	297..769	CDD:189008	126/544 (23%)
		ERAP1_C	846..1138	CDD:288671	3/13 (23%)
Rnpep	NP_112359.2	M1_LTA4H	24..484	CDD:341062	122/532 (23%)
		Substrate binding. /evidence=ECO:0000250	298..302		1/3 (33%)
		Leuk-A4-hydro_C	530..645	CDD:401171	10/69 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910