Protein Alignment CG46339 and npepps

DIOPT Version :10

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_001072690.1
• Gene: npepps / 780147
• XenbaseID: XB-GENE-1008338
• Length: 875
• Species: Xenopus tropicalis
• Alignment Length: 929
• Identity: 267/929 - (28%)
• Similarity: 425/929 - (45%)
• Gaps: 94/929 - (10%)

  Fly   283 PINRPL-KLYEGWRPLHYSLLIEPSVATSISNGSL--TIEIERDVSKVTSWEPIVLDVHNVSISN 344
            |..||. :|....||::|.|.::|.:......|.|  |:|::...::      ||::..::.|..
 Frog     2 PDRRPFERLPTDVRPVNYGLCLKPDLIDFTFEGKLEATVEVQNATNQ------IVMNCADIDIIT 60

  Fly   345 V-------RVIRALADGASNASEEQDLDFDSDYGEDNATFVINLSKTLAVETQLRVLLSLDFVSQ 402
            .       ..|.|......|..|:..|.|.|           .|.|...       :|.:|||.:
 Frog    61 ASYAPEGDEEIHATGFNYQNEDEKVTLSFPS-----------TLQKGAG-------MLKIDFVGE 107

  Fly   403 VTDTLQGIYKTSYTNPDTKNEEWMISTQFSPVDARRAFPCFDRPDMKANFSISIVRPMQFKMALS 467
            :.|.::|.|::.|... |....:...|||...||||||||:|.|.:||.|.:.::.|.. ::|||
 Frog   108 LNDKMKGFYRSKYATA-TGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDVILIVPKD-RVALS 170

  Fly   468 NMPKSGSRRF--RRGFIRDDFETTPKMPTYLVAFIVS--NMVDSRLASQDSGLTPRVEIWTRPQF 528
            ||.....:.:  ....:...|..||.|.||||||:|.  :.|::|  |.|..|   |.::|....
 Frog   171 NMNLIDRKPYPDDENLVEVKFARTPIMSTYLVAFVVGEYDFVETR--SSDGVL---VRVYTPVGK 230

  Fly   529 VGMTHYAYKMVRKFLPYYEDFFGIKNKLPKIDLVSVPDFGFAAMENWGLITFRDSALLV-PEDLQ 592
            .....:|.::..|.||:|:|:|.:...||||||:::.||...|||||||:|:|::|||: |::
 Frog   231 AEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKN-- 293

  Fly   593 LASSSEHMQVVAGIIAHELAHQWFGNLVTPKWWDDLWLKEGFACYMSYKALEHAHPEFQSMDTLT 657
              |.|...|.||.::.|||||||||||||.:||..|||.||||.::.|..::|..||:.......
 Frog   294 --SCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFV 356

  Fly   658 MLEFKESMEHDADNTSHAISFDVRSTNDVRRIFDPISYSKGTILLRMLNSIVGDVAFRSATRDLL 722
            ..::..:.|.||...||.|...|...::|..|||.||||||..::|||:..:||..||......|
 Frog   357 SADYTRAQELDALENSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDEDFRKGMNQYL 421

  Fly   723 KKFAYGNMDRDDLWAMLTRHGHEQGTLPKDLSVKQIMDSWITQPGYPVVNVERRGAD----LVLR 783
            .||...|...:|||..|     ||.:   ...:..:|::|..|.|:|::.||....:    |.|.
 Frog   422 TKFQEKNAATEDLWESL-----EQAS---GKPIAAVMNTWTKQMGFPLICVESEQKEDSVVLKLS 478

  Fly   784 QERYLLP-SKNTADQSTWFIPITFETDELRKGDNIPTHWMRSEDEEELIVGNVFAHSSNSDNVIY 847
            |:::... :.|:.|...|.:||:..|.|......:..  :..:.|..:::..|..|     ..:.
 Frog   479 QKKFCASGAPNSDDSYQWMVPISICTSESPASATVKI--LMDKPEMTVVLEGVKPH-----QWVK 536

  Fly   848 LNLNRQGYYRVNYDMT---SWLALKKNFSTLPRITRAQLLDDALHLSQAEYLTYDIPLTFLMELF 909
            ||....|:||..|..|   |.|...::.|..| :.|..|.:|...|::|..:. ...:..:||.|
 Frog   537 LNPGTVGFYRTQYSTTMLESLLPGIRDLSLQP-VDRLGLQNDLFSLARAGMIN-TAEVLKVMEAF 599

  Fly   910 DAVDDELLWIAAKPGLNYLIYNLKREPAYETFRAFMKFIVRPAFDHYGLHEPDNESHLQLKHRAL 974
            ....:..:|......|..|...|.....:|..:.|::.:..|.....|......|.||....|.|
 Frog   600 VNEPNYTVWSDLSCNLGILSTLLSHTDFHEEIQCFVRDVFSPIGQRLGWDPKPGEGHLDALLRGL 664

  Fly   975 VAYFACKFNYDRCTQKAQMKFREWMRDPKNNPIKPNLKSVIYCTSLAEGSSPEWYFAYKQYKTTT 1039
            |.....|..:....::|:.:|:|.:  ...|.:..:|:|.:|.|.|..|.:.......|.:|...
 Frog   665 VLGKLGKAGHQPTLEEARRRFKEHV--DGRNVLSADLRSPVYVTVLKHGDNSTLETMMKLHKQAD 727

  Fly  1040 SASEKEEILTSLGCTTKPWLLSKYLNMTINPTSGILKQDGALAFRAVASNA-IGHEIAFDFLQGN 1103
            ...||..|...||...:..|:.|.|:.::  :..:..||.......||..: :|.:.|::|::.|
 Frog   728 MQEEKNRIERVLGAIAEQDLIKKVLSFSL--SEDVRPQDTVCVIGGVAGGSKLGRKCAWNFVKDN 790

  Fly  1104 IKEIVEYYGDGFSTLSEMIK-SLTIYMNKDYHKHQLLDLAATCRK-LGLHAVESA---IELALEQ 1163
            .:|:...|..|| .:|.:|| ||..:.:.        .:||..:. ...|...||   ::...|.
 Frog   791 WEELYNRYQGGF-LISRLIKLSLDGFASD--------KMAAEIKAFFDAHPAPSAERTVQQCCEN 846

  Fly  1164 VNNNIYWRSHSYHSLKNFL 1182
            :..|..|......::.::|
 Frog   847 ILLNAGWLKRDAEAIHHYL 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	M1_APN-Q_like	297..764	CDD:341064	163/480 (34%)
		ERAP1_C	846..1126	CDD:463368	70/284 (25%)
npepps	NP_001072690.1	M1_APN-Q_like	17..455	CDD:341064	163/480 (34%)
		ERAP1_C	534..847	CDD:463368	77/327 (24%)