Protein Alignment CG46339 and CG4467

DIOPT Version :9

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Alignment Length: 1087
• Identity: 246/1087 - (22%)
• Similarity: 424/1087 - (39%)
• Gaps: 260/1087 - (23%)

  Fly   277 EDNTTKPIN------RPLKLYE-----GWRPLHYSLLIEPSVATSISNGSLTIEIERDVSKVTSW 330
            |:|.|:|.|      .|....|     ..|||.|.:.|.|::.|....|.:||::.  |.|.|::
  Fly   114 EENNTQPFNPIATNGEPFPWLEKMLPTSVRPLRYMVTIHPNLTTLDVKGQVTIDLH--VEKETNF 176

  Fly   331 EPIVLDVHNVSISNVRVIRALADGASNASEEQDLDFDSDYGEDNATFVINLSKTLA--------V 387
              |||.:.:::::...::.....|                      :.:.:.|.|.        :
  Fly   177 --IVLHIQDLNVTEKAIVTPGPKG----------------------YALKIVKVLEFPPRQQLYI 217

  Fly   388 ETQLRV------LLSLDFVSQVTDTLQGIYKTSYTNPDTKN--EEWMISTQFSPVDARRAFPCFD 444
            |.:.|:      .|:|.:.|::....:|.|...|   ::.|  |..:.:|.|.|..|||||||||
  Fly   218 EVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQY---ESSNGVERLLAATVFRPNGARRAFPCFD 279

  Fly   445 RPDMKANFSISIVRPMQFKMALSN----MPKSGSRRFRRGFIRDDFETTPKMPTYLVAFIVSNM- 504
            .|.::|.|.||:.|. :|.:.|||    ..:........|.:||||..||.:|...||::||:.
  Fly   280 EPHVRAPFRISVFRD-RFHIGLSNSIVHTTEDVGFYMGTGLLRDDFIETPPLPADAVAWVVSDFQ 343

  Fly   505 ----------VDSRLASQDSG-----------------------------------LTPRVEI-- 522
                      :.:..|...||                                   ||||..:
  Fly   344 RESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKNPPVRNITALTHSLNVNLTPRQNLTV 408

  Fly   523 --------WT-------RP-------QFVG--------MTHYAYKMV-----------RKFLPYY 546
                    |.       :|       |..|        .|.||.:.:           |..|.|.
  Fly   409 VQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRAPSYTFYAPRDLLIRSSFILHTSRDVLEYL 473

  Fly   547 EDFFGIKNKLPKIDLVSVPDFGFAAMENWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHEL 611
            :.:..|...|.|:|.|::|......:.:.||:|.:.|.|..|..:    :||..|..|..||..:
  Fly   474 QTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLKTSFLTDPSSI----TSEQYQFSALRIAEAM 534

  Fly   612 AHQWFGNLVTPKWWDDLWLKEGFACYMSYKALEHAHPEFQSMDTLTMLEFKESMEHDA----DNT 672
            ..|:||.:.:.|...|:||.||...|:...||......:...:...:.....:::.||    |:.
  Fly   535 VRQFFGGITSRKVLKDVWLWEGLIQYLGIHALAPLQETWPLREMYLLKMATAALDIDAIQGWDSI 599

  Fly   673 SHAISFDVRSTNDVRRIFDPISYSKGTILLRMLNSIVGDVAFRSATRDLLKKFAYGNMDRDDLWA 737
            .:..|.|..:        :.....|...:..||::.:|:..||......||...:...:..|||.
  Fly   600 MNGTSHDGNN--------EEFFVQKTAAIFSMLHTAIGEDRFRGCLGSFLKVNRFRTAEPTDLWT 656

  Fly   738 MLTRHGHEQGTLPKDLSVKQIMDSWITQPGYPVVNVERRGADLVLRQERYL-------------- 788
            :.|:..:      ...::|.:|..|..|||:|::.|.:.|..:.:.|..:.
  Fly   657 ICTKKAN------GSKNIKDMMTLWTHQPGFPLLTVTKMGNSISISQRPFRPAEFLAIHDDSYDG 715

  Fly   789 ------------LPS----------KNTADQSTWFIPITFETDELRKGDNI-PTHWMRSEDEEEL 830
                        :||          ...|....|..|:|:.||.    :|: .|.||::.|
  Fly   716 NNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKWIFPVTYVTDI----NNVSETLWMQNVD---- 772

  Fly   831 IVGNVFAHSSNSDNVIYLNLN--RQGYYRVNYDMTSWLALKKNFSTLP-RIT---RAQLLDDALH 889
            :..||      .:||.::.:|  :.|||||.|:..:|.:|.:..:..| |.|   |..:|.||..
  Fly   773 VTFNV------PENVKWIKVNAIQNGYYRVVYNDDNWASLIEELAANPNRFTSEDRLGMLSDAFT 831

  Fly   890 LSQAEYLTYDIPLTFLMELFDAVDDELLWIAAKPGLNYL-----IYNLKREPAYETFRAFMKFIV 949
            |..|..|    |....|.:...:..|..:......|.:|     |  ||....:.....|:|..:
  Fly   832 LCHANLL----PCEITMNMIQYLPSETHYGPMALALRHLEKWRRI--LKYSECFLMLSEFIKMKI 890

  Fly   950 RPAFDHYGLHEPDNESHLQLKHRALVAYFACKFNYDRCTQKAQMKFREWMRDPKNNPIKPNLKSV 1014
            ....:..|..:..:.:...|:...|:|....: :.|..| ||:....:::. .....|.|||:.|
  Fly   891 STVMEKVGWSDDGDVATRLLRPEVLLASVLWE-DIDSIT-KAKNMLNQYLY-YNGTAIPPNLREV 952

  Fly  1015 IYCTSLAEGSSPEWYFAYKQY----KTTTSASEKEEILTSLGCTTKPWLLSKYL-NMTINPTSGI 1074
            :|..|:..|....|...::::    :|:.:..|:.::|.:||.|...||.::.| ::|:.||..:
  Fly   953 VYTGSILSGEYIYWQHCWERFVNLQRTSETFVERMQLLRALGRTKDAWLQNRLLSHVTMLPTEEV 1017

  Fly  1075 LKQDGALAFRAVASNAIGHEIAFDFLQGNIKEIVEYYGDGFSTLSEMIKSLTIY--MNKDYHKHQ 1137
            ::     ..:|:|....|..:|..|||....|:.:..|.|..:.:::|.::|.|  ...||.
  Fly  1018 VQ-----VLKAIAGTPTGGAMACRFLQAKWFELEKRLGPGTISFAKVISAITQYGATKFDYD--- 1074

  Fly  1138 LLDLAATCRKLGLHAVESAIELALEQVNNNIYWRSHSYHSLKNFLEG 1184
              :|.:...:.|.....|.:.:.|..|.:|:.|.:.|..||..::||
  Fly  1075 --ELKSLVHRFGRGHGMSVLNMTLSSVASNVEWVARSQTSLYKWVEG 1119

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	Peptidase_M1	296..698	CDD:279741	114/514 (22%)
		M1_APN_2	297..769	CDD:189008	131/584 (22%)
		ERAP1_C	846..1138	CDD:288671	73/309 (24%)
CG4467	NP_001036747.1	Peptidase_M1	138..593	CDD:279741	111/488 (23%)
		GluZincin	145..682	CDD:301352	131/584 (22%)
		ERAP1_C	784..1078	CDD:288671	74/312 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020