Protein Alignment CG46339 and lta4h

DIOPT Version :9

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_998451.1
• Gene: lta4h / 406575
• ZFINID: ZDB-GENE-040426-2477
• Length: 611
• Species: Danio rerio
• Alignment Length: 645
• Identity: 139/645 - (21%)
• Similarity: 226/645 - (35%)
• Gaps: 195/645 - (30%)

  Fly   267 PVVEPAA-GEVEDNTTKPINRPLKLYEGWRPLHYSLLIEPSVATSISNG--SLTIEIERDVSKVT 328
            ||.:|:: ..:...:||               |.:|:........:..|  :||:|:..|
Zfish     3 PVSDPSSFSSLSKCSTK---------------HLNLIYHVDFDRHVLKGKVALTVEVLED----- 47

  Fly   329 SWEPIVLDVHNVSISNVRVIRALAD---GASNASEEQDLDFDSDYGEDNATFVINLSKTLAVETQ 390
            .:..:.||..::.||.|......|.   ||.:..:...|:.         |....||:...|..:
Zfish    48 KFSSLTLDSKDLKISKVSANGQAAKFELGAKHKFKGSPLEI---------TLPFELSRGQHVIVE 103

  Fly   391 LRVLLSLDFVSQVTDTLQGIYKTSYTNPDTKNEEWMISTQ---------FSPVDA---RRAFPCF 443
            :.                  |:||   |.....:|:...|         ||...|   |...||.
Zfish   104 IE------------------YETS---PTATALQWLTPKQTAGKKHPYLFSQCQATHCRTMVPCQ 147

  Fly   444 DRPDMKANFSISIVRPMQFKMALSNM-------PKSGSR---RFRRGFIRDDFETTPKMPTYLVA 498
            |.|.:|..:...:..|.:....:|.:       |...||   |||        :..| ||:||:|
Zfish   148 DTPSVKHTYYAQVSVPRELVALMSALRDGQEPDPSDSSRVIYRFR--------QPVP-MPSYLIA 203

  Fly   499 FIVSNMVDSRLASQDSGLTPRVEIWTRPQFVGMTHYAYKMVRKFLPYYEDFFGIKNKLPKI---- 559
            .:|     ..|.|::.|  ||..:|:..::|....|.:......|...|...|     |.:
Zfish   204 IVV-----GALESREIG--PRSRVWSEKEYVDEAAYEFAETETMLKTAESLAG-----PYVWGQY 256

  Fly   560 -DLVSVPDFGFAAMENWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHELAHQWFGNLVTPK 623
             .||..|.|.:..||| ..:||....:|..:           :.:||:||||::|.|.|||||.:
Zfish   257 DVLVLPPSFPYGGMEN-PCLTFVTPTVLAGD-----------RSLAGVIAHEISHSWTGNLVTNR 309

  Fly   624 WWDDLWLKEGFACYM--------------------SYKALEHAHPEFQSMDTLTMLEFKESMEHD 668
            .|:..||.||...|:                    .:|.|..:..:|.:.:.||.| .....|.|
Zfish   310 TWEHFWLNEGHTVYIERMIARCMEGEQLRQFKGIGGWKELHESVKQFGANNVLTNL-VPNLHEVD 373

  Fly   669 ADNTSHAISFDVRSTNDVRRIFDPISYSKGTILLRMLNSIV-GDVAFRSATRDLLKKFAYGNMDR 732
            .|..                 |..:.|.||..||..|..:: |...|....:..::.||||::..
Zfish   374 TDEA-----------------FSSVPYEKGFALLYHLEELMGGPEVFMGFVKSYIQLFAYGSVTT 421

  Fly   733 DDLWAMLTRHGHEQGTLPKDLSVKQIMDSWITQPGYPVVN------------------VERRGAD 779
            ::....|..:..::    .|:..|...::|:..||...|.                  |:.:.||
Zfish   422 EEWKNYLFTYFKDK----VDILNKVDWNAWMHTPGMAPVRPQYDTTMADACTSLCQKWVKAKEAD 482

  Fly   780 LVLRQERYLLPSKNTADQSTWFIPITFETD-----------ELRKGDNIPT-----HWMR 823
            |....|..:  .:..:.|...|:.:..:.|           |:.|.:||..     .|:|
Zfish   483 LASFTEADV--KQLNSPQLIEFMALLLQEDPLPLSHVKKMGEVYKLNNIKNAEVRFRWLR 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	Peptidase_M1	296..698	CDD:279741	102/453 (23%)
		M1_APN_2	297..769	CDD:189008	119/524 (23%)
		ERAP1_C	846..1138	CDD:288671
lta4h	NP_998451.1	leuko_A4_hydro	18..607	CDD:274120	136/630 (22%)
		M1_LTA4H	18..449	CDD:189006	119/535 (22%)
		Leuk-A4-hydro_C	467..606	CDD:286244	14/76 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910