Protein Alignment CG46339 and Rnpep

DIOPT Version :9

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_663392.2
• Gene: Rnpep / 215615
• MGIID: 2384902
• Length: 650
• Species: Mus musculus
• Alignment Length: 566
• Identity: 134/566 - (23%)
• Similarity: 201/566 - (35%)
• Gaps: 152/566 - (26%)

  Fly   427 ISTQFSPVDARRAFPCFDRPDMKANFSISIVRPMQFK--MALSNMPKSGSRRFRRGFIRDDFETT 489
            :.||...|..|..|||||.|.:|..:|..|..|..|.  |:.....|.|..:|       .|:.:
Mouse   166 VYTQGQAVLNRAFFPCFDTPAVKCTYSALIEVPDGFTAVMSADTWEKRGPNKF-------FFQMS 223

  Fly   490 PKMPTYLVAFIVSNMVDSRLASQDSGLTPRVEIWTRPQFVGMTHYAYK-MVRKFLPYYEDFFGIK 553
            ..:|:||:|..:.:     |||.:.|  ||..:|..|..:......|. ::.:||...|..||
Mouse   224 HPIPSYLIALAIGD-----LASAEVG--PRSRVWAEPCLIEAAKEEYSGVIEEFLATGEKLFG-- 279

  Fly   554 NKLP----KIDLVSV-PDFGFAAMENWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHELAH 613
               |    :.||:.: |.|.|..||| ..:||....||..:           :.:|.:|.||::|
Mouse   280 ---PYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPCLLAGD-----------RSLADVIIHEISH 329

  Fly   614 QWFGNLVTPKWWDDLWLKEGFACY-----------MSYKALEHA--------HPEFQSMDT-LTM 658
            .|||||||...|.:.||.|||..|           .:|..||.|        |......:. |..
Mouse   330 SWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMNVSGEENPLNK 394

  Fly   659 LEFKESMEHDADNTSHAISFDVRSTNDVRRIFDPISYSKGTILLRMLNSIVGDV-AFRSATRDLL 722
            |..|.....|.|:|                 ::...|.||...:..|..:|||. .|....:..:
Mouse   395 LRVKIEPGVDPDDT-----------------YNETPYEKGYCFVSYLAHLVGDQDQFDKFLKAYV 442

  Fly   723 KKFAYGNMDRDDLWAMLTRHGHEQGTLPKDLSVKQI----MDSWITQPGYPVVNVERRGADLVLR 783
            .:|.:.::..:|.......:..|.    |...|..|    .|.|:..||:|.
Mouse   443 DEFKFQSILAEDFLEFYLEYFPEL----KKKGVDSIPGFEFDRWLNTPGWPP------------- 490

  Fly   784 QERYLLPSKNTADQSTWFIPITFETDELRK-GDNIPTHWMRSEDEEELIVGNVFAHSSNSDNVIY 847
                             ::|.....|.|.| .:.:...|:.||.:.:.|..
Mouse   491 -----------------YLPDLSPGDSLMKPAEELAELWVTSEPDMQAIEA-------------- 524

  Fly   848 LNLNRQGYYRVNYDMTSWLA--------LKKNFSTLPRITRAQLLDDALHLSQAEYLTYDIPLTF 904
            :.::....|::.|.:...|.        :||...|.|:|:.||..:..|...|. .|..|
Mouse   525 VAISTWKTYQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQI-ILKND----- 583

  Fly   905 LMELFDAVDDELLWIAAKPGLNYLIYN-------LKREPAYETFRA 943
            ..|.|..|.| .|....|......:|:       :.|..|.:||.|
Mouse   584 YQEEFQKVKD-FLQSQGKQKYTLPLYHAMMGGSEMARTLAKDTFAA 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	Peptidase_M1	296..698	CDD:279741	82/298 (28%)
		M1_APN_2	297..769	CDD:189008	99/374 (26%)
		ERAP1_C	846..1138	CDD:288671	26/113 (23%)
Rnpep	NP_663392.2	leuko_A4_hydro	24..634	CDD:274120	134/566 (24%)
		M1_LTA4H	24..484	CDD:189006	97/369 (26%)
		Substrate binding. /evidence=ECO:0000250	298..302		1/3 (33%)
		Leuk-A4-hydro_C	504..644	CDD:286244	30/146 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910