Protein Alignment CG46339 and T12E12.6

DIOPT Version :9

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_500831.2
• Gene: T12E12.6 / 188454
• WormBaseID: WBGene00020465
• Length: 641
• Species: Caenorhabditis elegans
• Alignment Length: 663
• Identity: 176/663 - (26%)
• Similarity: 269/663 - (40%)
• Gaps: 141/663 - (21%)

  Fly   296 PLHYSLLIE----------PSVATSISNGSLTIEIERDVSKVTSWEPIVLDVHNVSISNVRVIRA 350
            ||.|.||.:          .|:....:..||:..|..|          .:|:|  |..|:.:||:
 Worm    24 PLSYDLLFKLPIHEFNGFTGSMVLHFNLSSLSDNITLD----------AVDLH--SFRNISLIRS 76

  Fly   351 LADGASNASEEQDLDFDSDYGEDNATFVINLSKTLAVETQLRVLLSLDFVSQVTDTLQGIYKTSY 415
                             :|..|.....:    |.|..:.:|:...|| |..|...|: |.|....
 Worm    77 -----------------ADLTEPTLKSI----KILKEKVELKFEKSL-FPGQYLLTI-GEYNGRI 118

  Fly   416 TNPD----TKNEEWMISTQFSPVDARRAFPCFDRPDMKANFSISIVRPMQFKMALSNMPKSGSRR 476
            .|..    .:....:.:|...|..|||.|||.|.|.:||.|.:|||.|.. .:|.||........
 Worm   119 GNSSEALFERRNPLLYTTHLQPNHARRLFPCIDHPAVKALFRLSIVHPTD-TVAQSNTIAMDVHV 182

  Fly   477 FRRGFIRDDFETTPKMPTYLVAFIVSNMVDS--RLASQDS-GLTPRVEIWTRPQFVGMTHYAYKM 538
            ..|.:.|..|:.||.:|.|||||.|  |.||  :|:.|.| |:|.||...:|...:.:...|
 Worm   183 ENRKWQRTIFQATPLLPAYLVAFSV--MPDSNLQLSRQTSFGVTVRVNGESRGLVLRVLDCA--- 242

  Fly   539 VRKFLPYYEDFFGIKN---KLPKIDLVSVPDFGFAAMENWGLITFRDSALLVPEDLQLASSSEHM 600
                |..:|...|:.:   .|.|||.:.||::. ..|||||.||..::         ||:|.:..
 Worm   243 ----LASFEILAGLIDVPLPLNKIDFILVPEYD-GGMENWGHITVSET---------LATSGDDA 293

  Fly   601 QVVAGIIAHELAHQWFGNLVTPKWWDDLWLKEGFACYMSYKALEHAHPEFQSMDTLTMLEFKE-S 664
            .::. :||||:||.|.||..|...|:.:.|:|....:|:.||::....:...:....:.::.| .
 Worm   294 HLIY-LIAHEIAHHWIGNRATIDSWNWICLQEDLTDWMALKAVKALLTDEIRLQRFQLAQYVEIQ 357

  Fly   665 MEHDADNTSHAISFDVRSTNDVRRIFDPISYSKGTILLRMLNSIVGDVAFRSATRDLLKKFAYGN 729
            :..|..:..|::....:...:   :.:...|.||.:||..|.|:||:....|..:.|:...:..|
 Worm   358 LVEDFLSPGHSLYMPSKINQE---LINRHCYLKGVVLLDTLESVVGEQFMYSVIKSLVGSHSTYN 419

  Fly   730 MDRDDLWAMLTRHGHEQGTLPKDLSVKQIMDSWITQPGYPVVNVERRGADLVLRQ-ERYLLPSKN 793
            :      ...|.: .:|..:.::.:|.||.:.|.|..|||.:.||..|....|:| .|.|.|.|.
 Worm   420 L------TTFTSY-FDQIRVDRNATVGQIYEYWYTTGGYPSILVENNGPSSRLQQLSRPLWPLKM 477

  Fly   794 TADQSTWFIP-ITFETDELRKGDNIPTHWMRSEDEEELIVGNVFAHSSNSDNVIYLNLNRQGYYR 857
            |   ||..|| ..|....:...:|.|                           :.:|||...:.|
 Worm   478 T---STLAIPQFVFSESIVFASENAP---------------------------LLVNLNFTSFMR 512

  Fly   858 VNYDMTSWLALKKNFSTLPR----ITRAQLLDDALH------------LSQAEY-LTYDIPLTFL 905
            ||||..:|.|:.|.....|.    :.||||:.|..:            |.:|.. :.|..|
 Worm   513 VNYDSLTWTAIFKYMFEEPELFSAVGRAQLVSDFCYFYANDKVDNGTILKEAVVDMVYSKP---- 573

  Fly   906 MELFDAVDDELLW 918
             |.|:..|..|.|
 Worm   574 -EFFELCDWNLYW 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	Peptidase_M1	296..698	CDD:279741	112/422 (27%)
		M1_APN_2	297..769	CDD:189008	130/492 (26%)
		ERAP1_C	846..1138	CDD:288671	26/90 (29%)
T12E12.6	NP_500831.2	GluZincin	25..402	CDD:387391	119/435 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020