Protein Alignment CG46339 and R03G8.6

DIOPT Version :10

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_510175.1
• Gene: R03G8.6 / 181438
• WormBaseID: WBGene00011000
• Length: 747
• Species: Caenorhabditis elegans
• Alignment Length: 644
• Identity: 177/644 - (27%)
• Similarity: 274/644 - (42%)
• Gaps: 140/644 - (21%)

  Fly   266 IPVVEPAAGEVEDNTTKPINRPLKLYEGWRPLHYSLLIE---PSVATSISNGSLTIE----IERD 323
            :.:::|.|.|::.......:..|..:..  |.||.:.|:   |..........:|.|    |..|
 Worm    10 LAIIKPFASELDARIADVASYRLPRHVS--PSHYDIHIKTYLPGYGWKADENKITFEGNVNILLD 72

  Fly   324 VSKVTSWEPIVL--------------DVHNVSISNVRVIRALADGASNASEEQDLDFDSDYGEDN 374
            :.:.|  :.:||              |..|||||:..|          .:|.|.|
 Worm    73 IKETT--DKLVLHSSSLNIISATFQSDEQNVSISHWNV----------QTESQFL---------- 115

  Fly   375 ATFVINLSKTLAVETQLRVLLSLDFVSQV-TDTLQGIYKTSYTNPD---TKNEEWMISTQFSPVD 435
             ||.:|.:    |:.|....:.::|..:| ||.| |::.|:.|..|   ..|    .:|||..:.
 Worm   116 -TFYLNNT----VKVQSSAGIQINFQGKVRTDGL-GLFATNSTREDGTVMTN----FATQFETIF 170

  Fly   436 ARRAFPCFDRPDMKANFSISIVRPMQFKMALSNMPKSGSRRFRRGFIRDDFETTP-----KMPTY 495
            ||...||||.|:.||.:::|:..|.. ..||||..:..|:      :.||::||.     ||.:|
 Worm   171 ARNMIPCFDEPEFKATWNVSLEHPTG-STALSNGIEVESK------VNDDWKTTTYKKTLKMSSY 228

  Fly   496 LVAFIVSNMVDSRLASQDSGLTPRVEIWTRPQFVGMTHYAYKMVRKFLPYYEDFFGIKNKLPKID 560
            ::|..:.: :..:....::|:  |:.::|.|..:....:|..:.|..|..:|..|||:..:.|:|
 Worm   229 ILALFIGD-IQFKETILNNGV--RIRVYTDPVNIDRVDHALNISRIVLEGFERQFGIRYPMEKLD 290

  Fly   561 LVSVPDFGFAAMENWGLITFRDSALL-VPEDLQLASSSEHMQVVAGIIAHELAHQWFGNLVTPKW 624
            .|||.:|.|.|||||||:.....:|: .|.|            |..|:.||:||||||||||.|:
 Worm   291 FVSVQNFKFGAMENWGLVIHNAYSLIGDPMD------------VTEIVIHEIAHQWFGNLVTMKY 343

  Fly   625 WDDLWLKEGFACYMSYKALEHAHPEFQSMDTLTM--------------LEFKESMEHDADNTSHA 675
            ||.:||.||||.||:...|....|::| .||..:              |.|.:::....:|.:..
 Worm   344 WDHIWLNEGFASYMTSYGLTFLDPDYQ-RDTFYLNCQFNPQINDGGVSLNFGKNLSSVMNNAATV 407

  Fly   676 ISFDVRSTNDVRRIFDPISYSKGTILLRMLNSIVGDVAFRSATRDLLKKFAYGNMDRDDLWAMLT 740
                               |.||...:|||.:|.|...|..|.:..|:|..|.|:|.:||:....
 Worm   408 -------------------YMKGCSFVRMLENIFGTEYFNEAIKFYLEKNQYDNVDDNDLYEAFR 453

  Fly   741 RHGHEQGTLPKDLSVKQIMDSWITQPGYPVVNVERRGADLVLRQERYLLPS--KNTADQSTWFIP 803
            .......|..|...:::....|..|.|:|.:.|........|.|.....|.  .|..|.. |.||
 Worm   454 TSSETLDTNGKPFDIEKFARCWTHQNGFPTIQVSNDNGIATLTQSHLYEPQLMLNECDYK-WDIP 517

  Fly   804 ITF-ETDELRKGDNIPTHWM-RSEDEEELIVGNVFAHSSNSDNVIYLNLNRQGYYRVNY 860
            |.: |..|.|    :...|: |:....||:          :|:.:.:|.|..|||.|.|
 Worm   518 IWYQEPGEAR----VQMAWLNRNSTSLELV----------ADDSVIINANSIGYYEVLY 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	M1_APN-Q_like	297..764	CDD:341064	144/511 (28%)
		ERAP1_C	846..1126	CDD:463368	7/15 (47%)
R03G8.6	NP_510175.1	M1_APN-Q_like	39..477	CDD:341064	144/511 (28%)
		ERAP1_C	548..>608	CDD:463368	7/15 (47%)