Protein Alignment CG46339 and AC3.5

DIOPT Version :9

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_001256214.1
• Gene: AC3.5 / 179447
• WormBaseID: WBGene00007071
• Length: 1090
• Species: Caenorhabditis elegans
• Alignment Length: 1151
• Identity: 252/1151 - (21%)
• Similarity: 446/1151 - (38%)
• Gaps: 278/1151 - (24%)

  Fly   155 SKACLIIAAFITVLALLFTIAITYFVTRQGLNPKEVTPPSCITADHPDVNATPIQTAGWVSMNSP 219
            |..||.:.|   |.|::|...:.:::|:|.....:                       :.|.|.
 Worm    79 SAICLFLLA---VAAIIFAAFLGHYLTKQNYEMMQ-----------------------FKSANE- 116

  Fly   220 PPLQAATPTPMASPTPTNTPTVTTTLAMPASSEKPEIRMVDPKVGDIPVVEPAAGEVEDNTT--K 282
                                ::||......|.:|.:         ||...|.|    ::|.:  :
 Worm   117 --------------------SMTTCKNFTRSHKKHQ---------DIVNEEDA----DENASIKQ 148

  Fly   283 PINRPLKLYEGWRPLHYSLLIEPSVATSISNGSL-----TIEIERDVSKVTSWEPIVLDVHNVSI 342
            |....|.|.:..:|:.|.:.:.|.|.   .||::     .:.||...:|      |||:..::..
 Worm   149 PTKEELALPKNVQPVWYDVSLSPKVG---GNGTMGLAHVKLNIEEPTNK------IVLNAKDIEF 204

  Fly   343 S-NVRVIR------------------------------ALADGASNASEEQDLDFDS--DYG--E 372
            : |:..|:                              |:|..|:..:.|......|  |.|  .
 Worm   205 TRNLEKIQLSKEVTKRAKKSVDSGTNSTSEMPEGSGEEAMATTATTTTTESTTPVSSFVDTGIKV 269

  Fly   373 DNATFVINLSK-TLAVETQLR----VLLSLDFVSQVTDTLQGIYKTSYTNPDTKNEEWMISTQFS 432
            .|..|..||.| ||.::.:|:    |:|.:.|.|:|::. .|:.:..|.|.:.| |:.|.:||.|
 Worm   270 TNIEFDENLEKVTLTLDQELKKGSTVVLKIPFTSKVSNN-NGLKEYKYKNSEGK-EQSMFTTQPS 332

  Fly   433 PVDARRAFPCFDRPDMKANFSISIVRPMQFKMALSNMPKSGSRRFRRGFIRDDFETTPKMPTYLV 497
            ....|..||.||:...||..:|:::. .:..:.::|   :|.:....|    |.:|:........
 Worm   333 YSYLRHVFPSFDQEAFKAPAAITLMH-SKGSIVVAN---TGVKTKDDG----DAQTSTLNKVLDP 389

  Fly   498 AFIVSNMVDSRLASQDSGLTPRVEIWTRPQFVGMTHYAYKMVRKFLPYYEDFFGIKNKLPKIDLV 562
            .|::.::|.|.: :..||:|  :.|||||:....|..:.....:.:...|.....:.:...:|:|
 Worm   390 DFVIGDLVASEV-NTTSGIT--IRIWTRPEVKHSTEQSLDYANQAIDAMEHILQSRLESKSLDIV 451

  Fly   563 SVPDFGFAAMENWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHELAHQWFGNLVTPKWWDD 627
            :||.|......:...|...:..:|..|.   ::.......:|.:|::.:|.||||.:..|:.:..
 Worm   452 AVPGFQTGNRVSPSFIVLPEEDILYNEQ---SNDINQKTRIARMISNRIAAQWFGGITNPEEFGT 513

  Fly   628 LWLKEGFACYMSYKALEHAHPEFQSMDTLTMLEFKESMEHDADNTSHAISF-DVRSTNDVRRIFD 691
            .||.|....::..:|||.. .:..| |.|...|.::.:|.||..||..:.. :|.|:.|:..|..
 Worm   514 FWLNEALPRFLEVEALEKI-LDINS-DDLWTYEMEKILERDATATSQPLRVKNVFSSADIAEIDH 576

  Fly   692 PISYSKGTILLRMLNSIVGDVAFRSATRDLLKKFAYGNMDRDDLWAMLTR--HGHEQGTLPKDLS 754
            .....||..:|||:...||...|..|.|..:..:.......|.||....:  .|..:|...:.|.
 Worm   577 EFIGKKGAAVLRMIQKSVGVNVFNKAIRSFVSSYRSAYPYDDGLWKSFEKALGGKLKGWNNEPLD 641

  Fly   755 VKQIMDSWITQPGYPVVNVERRGADLV-LRQERYLLPSKN---TADQ---------STWFIPITF 806
            |.:.:::|:.|.|:|:|:||:...:.| |.|||:    ||   |.:|         ..|.:|:
 Worm   642 VAKFVNTWVDQIGFPLVSVEKLDDETVELSQERF----KNDHKTKEQFKFRNAKYWFNWEVPL-- 700

  Fly   807 ETDELRKGDNIPTHWMRSEDEEELIVGNV-FAHSS-----NSDNVIYLNLNRQGYYRVNYDMTSW 865
                          :::|...    |||| :.|.:     |:.:.||||.:..|.|||||:...|
 Worm   701 --------------FLKSSGP----VGNVSWLHEAFRLPLNTSDSIYLNTDSNGVYRVNYEEKRW 747

  Fly   866 ----LALKKNFSTLPRITRAQLLDDALHLSQAEYLTYD---------------IPLTFLMELFDA 911
                ..|:|:...|...|||:|:.|...|:.:..|.::               :|......:|..
 Worm   748 NDIAKQLEKSHGKLSERTRARLISDVFALANSGALPFETALNVTSYLPMETATVPWLIATRIFKK 812

  Fly   912 VDDELLWIAAKPGLNYLIY-------------------NLKREPAYETFRAFMKFIVRPAFDHYG 957
            :.:.|.....:..||..||                   |..:...|......|. ||:|
 Worm   813 LTERLEGAPIQDKLNSFIYQKIHKKFEEISSSPGEASSNYLKNRLYANLLDLMA-IVKP------ 870

  Fly   958 LHEPDNESHLQLKHRALVA--YFACKFNYDRCTQKAQMKFREWMRDPKNNPIKPNLKSVIYCTSL 1020
              |..||...:|.....:|  .|:..|:.| |::                 :..:|:..:||..:
 Worm   871 --EKSNEKLNELFVEGFLAPCQFSGNFSSD-CSE-----------------VPGDLREKVYCNGV 915

  Fly  1021 AEGSSPEWYFAYKQYKTTTSASEKEEILTSLGCTTKPWLLSKYLNMTINPTSGILKQDGALAFRA 1085
            ..|:...:....:..:.....:||:.:..||.|...|..|.:.:...:|.||.:     .|..|.
 Worm   916 EFGNDTVFETVRELAEKEVDGAEKDLLQNSLACFRDPRALRRLILDNLNSTSTV-----TLLLRK 975

  Fly  1086 VASNAIGHEIAFDFLQGNIKEIV--EYYGD----------GFSTLSEMIKSLTIYMNKDYHKHQL 1138
            :.|..:|.|||.:::..|...::  ::..|          |....:|..||:.....:.:||
 Worm   976 MNSRPVGKEIATNWIIDNWSTVLKKKFKNDPETLNAIADAGIILDNEREKSMIETFMEHHHK--- 1037

  Fly  1139 LDLAATCRKLGLHAVESAIELALEQVNNNIYWRSHSYHSLKNFLEG 1184
                      ..|.:|| ::..:|:...:||||....:.|.::|:|
 Worm  1038 ----------STHGIES-LDKKIEEATTDIYWRKQKINELNDYLDG 1072

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	Peptidase_M1	296..698	CDD:279741	104/447 (23%)
		M1_APN_2	297..769	CDD:189008	123/519 (24%)
		ERAP1_C	846..1138	CDD:288671	72/343 (21%)
AC3.5	NP_001256214.1	Peptidase_M1	156..574	CDD:279741	104/444 (23%)
		GluZincin	165..656	CDD:301352	123/517 (24%)
		ERAP1_C	728..1052	CDD:288671	76/369 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020