Protein Alignment CG46339 and mnp-1

DIOPT Version :9

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_497878.1
• Gene: mnp-1 / 175564
• WormBaseID: WBGene00007139
• Length: 781
• Species: Caenorhabditis elegans
• Alignment Length: 821
• Identity: 165/821 - (20%)
• Similarity: 292/821 - (35%)
• Gaps: 228/821 - (27%)

  Fly   148 PPSGVYVSKA---CLIIAAFITVLALLFTIAITYFVTRQGLNPKEVTPPSCITADHPDV---NAT 206
            ||......||   .|:||....::.::....:..|:|....|           .|.||:   |||
 Worm     3 PPPASPSKKAKSSWLLIALIAVIIGIILCAGVITFLTLFNKN-----------GDGPDMDWQNAT 56

  Fly   207 --PIQTAGWVSMNSPPPLQAATP----TPMASPTPT--------------NTPTVTTTLAMP--A 249
              |:.|....::::.....|.||    |.:...|.|              :|.|:.||.|:|  .
 Worm    57 EVPLTTTSKATVSTTTTQSATTPSTTTTRIEETTTTTSGAFDESVKNSEASTSTIPTTEAVPTTT 121

  Fly   250 SSEKPEIRM-VD------PKVGDIPVVEPAAGEVE--DNTTKPINRPLKLYEG-WRPLHYSLLIE 304
            :::.|||.| ||      .|..|..:||..| |::  ..:..|...||..... ::|:||.|
 Worm   122 ATDAPEIVMPVDVASILKDKTKDFEIVEKCA-EIQALPVSCTPSQSPLTSDPSKFQPIHYVL--- 182

  Fly   305 PSVATSISNGSLTIEIERDVSKVTSWEPIV----------------LDVHNVSISN------VRV 347
                      ::||   |||.|     |::                :.:|:|.|.|      :.|
 Worm   183 ----------NITI---RDVRK-----PVLEGHMQLFASTKDQVQAISLHSVKIHNLENRDRIHV 229

  Fly   348 IRALADGASNASEEQDLDFDSDYGEDNATFVINLSKTLAVETQLRVLLSLD-FVSQVTDTLQGIY 411
            :..........|....:|           .:|:|....::.:.:.:.:.:| |:|  .|:...::
 Worm   230 VNCNTGETICVSRVHQID-----------DLIHLELAQSISSGVNLRVDIDGFIS--ADSGPHVF 281

  Fly   412 KTSYTNPDTKNEEW----MISTQFSPVDARRAFPCFDRPDMKANFSI-------------SIVRP 459
            |...|      .:|    ||.:.|.|..||..||.||..:.|:.|::             |::.|
 Worm   282 KQIPT------AKWRVPQMIGSVFEPTSARHVFPSFDLHNQKSTFNLCLNHGPSMSAIANSLINP 340

  Fly   460 MQFKMALSNMPKSGSRRFRRGFIRDDFETTPKMPTYL--VAFIVSNMVDSRLASQDSGLTPRVEI 522
                    |:..||...|.:        |.|.:...|  |||..:|.:.....:.|....|.:::
 Worm   341 --------NVSTSGISCFEK--------TVPLIAQQLSFVAFEKTNPLFYNTTTMDGAYLPEIDM 389

  Fly   523 WTRPQFVGMTHY--AYKMVRKFLPYYEDFFGIKNKLPKIDLVSVP-DFGFAAMENWGLITFRDSA 584
            ...........|  .:..|.|.:.....:.|....|.::::|..| ..|.:|:   |:||....|
 Worm   390 IFNLNAKNFKQYEWIHSEVSKVMALMSKWSGFSYPLTRLEIVVAPVQAGHSAL---GVITLPAQA 451

  Fly   585 LLVPEDLQLASSSEHMQVVAGIIAHELAHQWFGNLVTPKWWDDLWLKEGFACYMSYKALEHAHPE 649
            :...:     .:|.|..::..:|.     ||...:||.   :....::....|:.:|..|    |
 Worm   452 IAYQK-----HTSTHETLIKEVIG-----QWMEGVVTT---EHTCFEKALIAYVEWKINE----E 499

  Fly   650 FQSMDTLTMLEFKESMEHDADNTSHAI----SFDVRSTNDVRRIFDPISYSKGTILLRMLNSIVG 710
            .|.:.....:|..:....:.:.|:.::    ....:|:|.....|..:.|:        |:...|
 Worm   500 LQIVKKTRKMEVSKIRPRNLNETADSVRVLRQIKSQSSNLCSPRFVEVFYT--------LDETYG 556

  Fly   711 DVAFRSATRDLLKKFAYGNMDRDDLWA----MLTRHGHEQGTLPKDLSVKQIMDSWITQPGYPVV 771
            ........|.:..|||:......| ||    ..|....|.|.|         :..|.
 Worm   557 QETVIGMIRVIFDKFAFSTATISD-WASAAETATGGRPEAGAL---------IHQWY-------- 603

  Fly   772 NVERRGADLVLRQERYLLPSKNTAD-----QSTWFIPITFETDELRKGDNIPTHWMRSEDEEELI 831
                |.:..:.|.....:.|.|:.:     :.||.:|:.....   .|..:.   :.||.::.:
 Worm   604 ----RPSSTISRPVLRAVVSSNSVEFNQLTEETWTVPLEISGS---AGTQLA---VISEKKQAI- 657

  Fly   832 VGNVFAHSSNSDNVIYLNLNRQGYYRVNYDMTSWLALKKNF 872
               .|.   :||.|: ::..|:.:..|.||..::|.|.:.|
 Worm   658 ---PFV---SSDYVV-VDAGRKSHAFVVYDADTYLRLIRCF 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	Peptidase_M1	296..698	CDD:279741	85/450 (19%)
		M1_APN_2	297..769	CDD:189008	98/524 (19%)
		ERAP1_C	846..1138	CDD:288671	7/27 (26%)
mnp-1	NP_497878.1	Peptidase_M1	172..556	CDD:279741	86/467 (18%)
		GluZincin	<294..>480	CDD:301352	47/217 (22%)
		GluZincin	<547..602	CDD:301352	14/72 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010