Protein Alignment CG46339 and Y53F4B.20

DIOPT Version :10

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_497105.3
• Gene: Y53F4B.20 / 175160
• WormBaseID: WBGene00013166
• Length: 694
• Species: Caenorhabditis elegans
• Alignment Length: 807
• Identity: 164/807 - (20%)
• Similarity: 284/807 - (35%)
• Gaps: 211/807 - (26%)

  Fly   278 DNTTKPINRPLK------------------LYEGWRPLHYSL--LIEPSVATSISNGSLTIEIER 322
            |:...||.:||.                  |:.|...:|:.:  .|.|..|....:.|....|:.
 Worm    29 DDRLPPILKPLSYDLQLQLPLSEVSDPDVPLFTGRCVMHFEINQQIGPESAFISDSTSNRARIKF 93

  Fly   323 DVSKVTSWE--PIVLDVHNVSISNVRVIRALADGASNASEEQDLDFDSDYGEDNATFVINLSKTL 385
            |:..:..:|  .:|::.|.:.|.||:    |.|.:...|.:|.:.|...|             ||
 Worm    94 DIIMLDHFENVSLVMNGHELEIFNVQ----LTDDSMELSVDQPVLFPGRY-------------TL 141

  Fly   386 AVETQLRVLLSLDFVSQVTDTLQGIYKTSYTNPDTKNEEWMISTQFSPVDARRAFPCFDRPDMKA 450
            .:.                 ..:|:..::....|. .|..:..:...|..|...||.:.....|.
 Worm   142 TIH-----------------RYKGLIGSAIYYRDA-GEHAVFGSNLFPNRAPAVFPSYLASTEKV 188

  Fly   451 NFSISIVRPMQFKMALSNMPKSGSRRFRRGFIRDDFETTPKMPTYLVAFIVSNMVDSRLASQDSG 515
            .|||::|.|:......|...:...|:....:....|.|||.:...::.|::.....:.:.|..:|
 Worm   189 TFSITMVHPVGTLALTSGSNEGAPRKIDENWQMTTFSTTPSITPSMLCFLLLPHEYTHIESTYTG 253

  Fly   516 LTPRVEIWTRPQFVGMTHYAYKMVRK------------FLPYYEDFFGIKNKLPKIDLVSVPDFG 568
            :...|            ||....|:|            .|...:|.|.....:||||::::.:..
 Worm   254 VNISV------------HYNRFRVQKEQTKHLLHTATQVLALLKDIFSSLIPVPKIDIITMNEVS 306

  Fly   569 FAAMENWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHELAHQWFGNLVTPKWWDDLWLKEG 633
            ..|.  :|.|        |..::|..|:....||  .::|..||.||.|.........:|.|:|.
 Worm   307 STAC--FGSI--------VVSEVQFFSADYANQV--KMLATWLAKQWIGGYAAISEGSELCLQED 359

  Fly   634 FACYMSYKALEH-AHPEFQSMDTLTMLEFKESMEHDADN---TSHAISFDVRSTNDVRRIFDPIS 694
            ...:::.|.::. .:.||..:..|..:...|::....|.   ..|...|:         ||:...
 Worm   360 LVAFIADKVIKRMTNDEFTRLGHLAKIYLSETIFTAGDTLKLDEHPNEFE---------IFEKCG 415

  Fly   695 YSKGTILLRMLNSIVGDVAFRSATRDLL---KKFAYGNMDRDDLWAMLTRHGHEQGTLPKDLSVK 756
            . ||..:|..:.|::|:.:..|...:::   ||.:|.:.         |.:|....|:.:|:.|.
 Worm   416 L-KGVAMLESIESLIGEKSMISKINEMIYNSKKGSYSSR---------TLYGLLNSTVDEDIYVS 470

  Fly   757 QIMDSWITQPGYPVVNVERRGADLVLRQERYLLPSKNTAD----QSTWFIPITFETDELRKGDNI 817
            |::..|....|.|.:||:|....:.:.|....:..||.|.    ...|.:|:.|...:|
 Worm   471 QLLHYWHEHGGLPYMNVDRLANSIKITQNGSNMTVKNGAGTWERMPLWPLPLKFTEFKL------ 529

  Fly   818 PTHWMRSEDEEELIVGNVFAHSSNSDNVIYLNLNRQGYYRVNYDMTSWLALKKNFSTLPRITRAQ 882
            |.         :::|.:....|...|.:|:.||....|||||||:.:|..:|
 Worm   530 PI---------QIMVSHGIHLSPIRDGLIFSNLGFTNYYRVNYDIDTWREIK------------- 572

  Fly   883 LLDDALHLSQAEYLTYDIPLTFLMELFDAVDDELLWIAAKPGLNYLIYNLKR--EPAYETFR-AF 944
                       ..||.:.....|.|.|..|.|...:           |::|.  |||....| .|
 Worm   573 -----------TVLTENATSYTLRERFQLVSDFCYF-----------YSIKSLPEPAASVLRNEF 615

  Fly   945 MKFI-VRPA---------FDHYGLHEPDNESHL------QLKHRALVAYFACKFNYDRCTQKAQM 993
            ::.: :||.         |.....||.....||      ||:.:.          :|.....::|
 Worm   616 VQLVRLRPTSFPICDAAIFQCVVTHEHTKPRHLDKSTMVQLRRKV----------FDSFANSSEM 670

  Fly   994 KFREWMRDPKNNPIKPNLKSVIYCTSL 1020
            :.|..:.....|.:         ||.|
 Worm   671 ECRAGLAHDALNDL---------CTKL 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	M1_APN-Q_like	297..764	CDD:341064	98/489 (20%)
		ERAP1_C	846..1126	CDD:463368	42/194 (22%)
Y53F4B.20	NP_497105.3	GluZincin	39..>300	CDD:472708	58/307 (19%)
		ERAP1_C	552..>593	CDD:463368	17/64 (27%)