Protein Alignment CG46339 and LOC1278415

DIOPT Version :10

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: XP_318000.5
• Gene: LOC1278415 / 1278415
• VectorBaseID: AGAMI1_009252
• Length: 1020
• Species: Anopheles gambiae
• Alignment Length: 982
• Identity: 258/982 - (26%)
• Similarity: 440/982 - (44%)
• Gaps: 112/982 - (11%)

  Fly   252 EKPEIRMVDPKVGDIPVVEPAAGEVEDNTTKPINRPLKLYEGWRPLHYSLLIEPSVATSISNGSL 316
            |:|::.......|.:     |:.|:.....:.::...:|.....|:||.|.:...:..:....:.
Mosquito    32 EEPQLPGASDLSGGV-----ASDEIGVAPAQAVDERYRLPTTSIPIHYDLHLRTEIHRNERTFTG 91

  Fly   317 TIEIERDVSKVTSWEPIVLDVHNVSISNVRVIRALADGASNA-SEEQDLDFDSDYGEDNATFVIN 380
            |:.|:..|.:.|  :.:|:....:.:|:.:| .:|.:|.:.| :...|:.:.:|...::.||.
Mosquito    92 TVGIQLQVVQAT--DKLVMHNRGLVMSSAKV-SSLPNGVTGAPTLIGDVQYSTDTTFEHITFT-- 151

  Fly   381 LSKTLAVETQLRVLLSLDFVSQVTDTLQGIYKTSYTNPDTKNEEWMISTQFSPVDARRAFPCFDR 445
             |.|:....  ..||.:.|..::.....|.|.:||. .|.....::.:|||....||.||||:|.
Mosquito   152 -SPTILQPG--TYLLEVAFQGRLATNDDGFYVSSYV-ADNGERRYLATTQFESTSARMAFPCYDE 212

  Fly   446 PDMKANFSISIVRPMQFKMALSNMPKSGSRRFRRGFIRDDFETTPKMPTYLVAFIVSNMVDSRLA 510
            |.:||.|::||.....:| |:||||:..............||.||.|.|||:||:|.:. ..||:
Mosquito   213 PGLKATFTVSITHSRSYK-AISNMPQKTFTDIETDMRTTFFEKTPAMSTYLLAFVVCDF-QIRLS 275

  Fly   511 SQDSGLTPRVEIWTRPQFVGMTHYAYKMVRKFLPYYEDFFGI--KNKLPKIDLVSVPDFGFAAME 573
            ...       .::.||..:....:|.:...|.|...:|..||  ...:||:|.:::|||...|||
Mosquito   276 GAQ-------RVYVRPNALNEATFALEAGVKILKVLDDHLGIPYDTYMPKLDQIAIPDFAAGAME 333

  Fly   574 NWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHELAHQWFGNLVTPKWWDDLWLKEGFACYM 638
            ||||:|:|:.|||..   ...|:......||..||||.|||||||||:|:||:.:||.||||...
Mosquito   334 NWGLVTYREQALLFN---PAVSTYRGKTNVATTIAHEYAHQWFGNLVSPEWWEYIWLNEGFATLY 395

  Fly   639 SYKALEHAHPEFQSMDTLTMLEFKESMEHDADNTSHAISFDVRSTNDVRRIFDPISYSKGTILLR 703
            .:.||:.|:|..:..:.......:.:|..|...::..::::..:..::..:||.::|.|...:|.
Mosquito   396 EFYALDMAYPGQEYWELFNQQVIQYAMGQDGQASTRPMNWNAATPGEISALFDRVAYDKSGSVLN 460

  Fly   704 MLNSIVGDVAFRSATRDLLKKFAYGNMDRDDLWAMLTRHGHEQGTLPKDLSVKQIMDSWITQPGY 768
            |:..::||..:::..:..|...|......:.|:|.|......:|.||..::|.|||.:|..:.||
Mosquito   461 MMRHVLGDDNWKAGLKAYLTDRALQGAVDEQLYAGLQSAIEGKGVLPNGVTVGQIMRTWTNEAGY 525

  Fly   769 PVVNVERR--GADLVLRQERYLLPSKNTADQSTWFIPITF---------ETDELRKGDNIPTHWM 822
            ||:||.|.  ..|:::.|||: ...:|..:.:.|.||..:         |.|:.:        |:
Mosquito   526 PVLNVRRSYDTGDVIISQERF-YNDRNVPNTNIWMIPYNYVHQAKADFNEFDDFQ--------WL 581

  Fly   823 RSEDE--EELIVGNVFAHSSNSDNVIYLNLNRQGYYRVNYDMTSW----LALKKNFSTLPRITRA 881
            .::..  |..:..|.:         |..|..:.||||||||..:|    .||.:|::::.|:.||
Mosquito   582 ATKAARIETTVPANEW---------IVFNKQQVGYYRVNYDERNWELITNALHENWASIHRLNRA 637

  Fly   882 QLLDDALHLSQAEYLTYDIPLTFLMELFDAVDDELLWIAAKPGLNYLIYNLKREPAYETFRAFMK 946
            ||:|||..|:::..|...:.|.|:..|.:. .:...|.||...|.|....|:....|..|..|:.
Mosquito   638 QLIDDAYWLARSGRLDLRVALRFMTYLRNE-REYAPWTAANVALTYFNNRLRGTAEYHNFLIFVD 701

  Fly   947 FIVRPAFDHYGL-----HEPDNESHLQLKHRALV---AYFACKFNYDRCTQK--AQMKFREWMRD 1001
            .::.   |.|.|     ..||:    .|.|:.||   :.:||...|..|..|  |.:|.......
Mosquito   702 ALIE---DIYSLLTIDAVSPDD----TLLHKYLVQTISTWACSMGYTDCLMKTAALLKAEASGTG 759

  Fly  1002 PKNNPIKPNLKSVIYCTSLAEGSSPEWYFAYKQYKTTTSASEKEEILTSLGCTTKPWLLSKYLNM 1066
            |   .:.|::.||.||..:......|:.:.|::...:.:.:|:..::.||||:.....|..:|..
Mosquito   760 P---AVHPDIASVTYCYGMRSALESEFQYLYRKMMNSKNLAERTMLIDSLGCSNNKEFLKAFLTT 821

  Fly  1067 TINPTSGILKQDGALAFRA----------VASNAIGHEIAFDFLQ--GNIKEIVEYYGDGFSTL- 1118
            .:...:|:     .:.:||          .:....|.:...:||.  ..:.|.|       |||
Mosquito   822 ALGSGTGV-----EINYRADERRRVVQAIYSGGRTGVDALIEFLMDPALVNEFV-------STLS 874

  Fly  1119 -SEMIKSLTIYMNKDYHKHQLLDLAATCRKLGLHAVESAIELALEQVNNNIYW-RSHSYHSLKNF 1181
             |.:..:|:...::..:..::..|.|....||.................|:.| .......|.||
Mosquito   875 TSTLNSALSAIASRTNNVEEMNKLNALITALGSRVNSQTAANLRTTAQANLDWVNGFEGLMLSNF 939

  Fly  1182 LEGIVSE 1188
            |....:|
Mosquito   940 LAEFAAE 946

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	M1_APN-Q_like	297..764	CDD:341064	140/469 (30%)
		ERAP1_C	846..1126	CDD:463368	79/307 (26%)
LOC1278415	XP_318000.5	None