Protein Alignment CG46339 and lvrn

DIOPT Version :10

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: XP_031748993.1
• Gene: lvrn / 100496094
• XenbaseID: XB-GENE-980447
• Length: 990
• Species: Xenopus tropicalis
• Alignment Length: 1003
• Identity: 276/1003 - (27%)
• Similarity: 460/1003 - (45%)
• Gaps: 156/1003 - (15%)

  Fly   278 DNTTKPINRP-----LKLYEGWRPLHYSLLIEPSV-ATSISNGSLTIEIERDVSKVTSWEPIVLD 336
            :|..:|.:||     |:|.....||||.|.:.|.: .....|...:.::...:|.|...:.::|.
 Frog    55 ENIAEPTDRPGIWNNLRLPHNLVPLHYDLELWPRMEEDEEGNYPFSGQVNITISCVEDTDVVLLH 119

  Fly   337 VHNVSISNVRVIRALA-----------DGASNASEE-------QDLDFDSDYG----------ED 373
            ...::.|:|. :|.|.           ||..||.:|       ||..:|...|          ||
 Frog   120 SIQLNFSDVG-LRLLGNKTIMYQSMEKDGKHNALQEGRAYKRLQDPTYDIHGGNVSINNVWTFED 183

  Fly   374 NATFVINLSKTLAVETQLRVLLSLD---FVSQVTDTLQGIYKTSYTNPDTKNEEWMISTQFSPVD 435
            ::..|:.|::.|....  ..||.|:   |:.|.|    .::.|.|  .|...::.::::...|..
 Frog   184 HSYVVLELNERLVAGN--LYLLELNYTGFIRQNT----ALFITHY--KDFNIDKAVVASLLEPEY 240

  Fly   436 ARRAFPCFDRPDMKANFSISIVRPMQFKMALSNMPKSGSRRFRRGFIRDD----------FETTP 490
            ||..:||||.|.:||.|.|.:|....: :||||||......      |:|          |:|||
 Frog   241 ARAVYPCFDEPALKATFKIRLVHNSSY-VALSNMPAVAVSE------REDIDGSIWTVTTFDTTP 298

  Fly   491 KMPTYLVAFIVSNMVDSRLASQDSGLTPRVEIWTRPQFV--GMTHYAYKMVRKFLPYYEDFFGIK 553
            ||.||:.||::.:.....:..:.:    .:.:|.|.:.|  |....|..:....|.|.||.|.:.
 Frog   299 KMSTYITAFVICDFDYVNITERGN----EIRVWARKEVVQKGFASLALSIAGPLLSYMEDLFNVS 359

  Fly   554 NKLPKIDLVSVPDFGFAAMENWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHELAHQWFGN 618
            ..|.|.|.|::||....||||||||||.:.||:. :..|.:|:|:....:  |::||:|||||||
 Frog   360 YPLQKTDFVALPDLDVEAMENWGLITFIEEALIY-DPRQKSSNSKFRTSL--IVSHEIAHQWFGN 421

  Fly   619 LVTPKWWDDLWLKEGFACYMSYKALEHAHPEFQSMDTLTMLEFKESMEHDADNTSHAISFDVRST 683
            |||.|||.||||.||||.||.|..:.....:.:..:..||...:...|.|..  :||.:..::..
 Frog   422 LVTMKWWTDLWLNEGFATYMEYFGITFLDSKLELNELFTMHNLQPIFERDVG--AHAKTVSMKEE 484

  Fly   684 N----DVRRIFDPISYSKGTILLRMLNSIVGDVAFRSATRDLLKKFAYGNMDRDDLWAMLTRHGH 744
            .    |...:|:..:|.||:.|:|||:|.:.:..|.......||.|::.|:|:||||..|.....
 Frog   485 ELYEADSSHMFNEFTYDKGSALVRMLSSFLTEKLFIKGISSYLKTFSFSNVDQDDLWNHLQMFID 549

  Fly   745 EQGTLPKDLSVKQIMDSWITQPGYPVVNVERRGADLVLRQERYLLPSKN--TADQS-TWFIPITF 806
            .|..:....:::.||.||..|.|.|::.::....:|.  :|.:...:.:  |:|.: ||.:|:|:
 Frog   550 HQDEVRLPTTLRHIMQSWTWQRGIPLLTLDTTTGELA--EELFKTDNTDNITSDSNHTWIVPVTW 612

  Fly   807 ETDELRKGDNIPTHWMRSEDEEELIVGNVF-AHSSNSDNVIYLNLNRQGYYRVNYDMTSWLALKK 870
                ::.|....:.|:.|:.:       || ..::.:|..|.||:|..||||.||:..:|..|.|
 Frog   613 ----MKNGTKQISLWLDSKSK-------VFPVLTTAADEWIVLNINVTGYYRTNYNKENWNRLAK 666

  Fly   871 ----NFSTLPRITRAQLLDDALHLSQAEYLTYDIPLTFLMELFDAVDDELLWIAAKPGLNYLIYN 931
                |...:|.:.|.||::||..|::..|..:...|: |.:..:..::..:|......:....|.
 Frog   667 QLEANPKVVPTVNRIQLIEDAFILARYGYTDHGTALS-LTKYLEKEEEINVWYTVLKHVTSSDYP 730

  Fly   932 LKREPAYETFRAFMKFIVR---PAFDHY------GLHEPDNESHLQLKHRALVAYFACKFNYDRC 987
            |   ..|..|..|.|:|::   |.:..:      ...|..::..:|: |..|:...||.|....|
 Frog   731 L---ITYTNFPLFKKYILKRISPIYQRFANSIRRNFDEAADDYFIQV-HIELILKTACSFGLQDC 791

  Fly   988 TQKAQMKFREWMRDPKNNPIKPNLKSVIYCTSLAEGSSPEWYFAYKQYKTTTSASEKEEILTSLG 1052
            .|.|...:..||::...|.|..::::.|.|.::|.|...||.||:|....:... |::.:..:|.
 Frog   792 LQLAHQLYATWMKNCSGNVIPESIRNPICCYAIANGGEKEWEFAWKMVNKSEEI-ERDLLFYALS 855

  Fly  1053 CTTKPWLLSKYLNMTINPTSGILKQDGALAFRAVASNAIGHEIAFDFLQGNIKEIVEYYG----- 1112
            ||.:||||.:||..::.    :.|......|..|..|.||..||::||:.|.:.|.:.:|
 Frog   856 CTKEPWLLHRYLEYSLE----MYKSSAFTIFLDVIKNEIGRHIAWEFLKENWQRIHDIFGPRDTV 916

  Fly  1113 DGFSTL---------SEM-IKSLTIYMNKDYHKHQLLDLAATCRKLGLHAVESAIELALEQVNN- 1166
            |.::.|         |:: .:.:.:::|...:::|.                   |..||||.|
 Frog   917 DFYTVLLPTFASKAASDLQFQEIQLFINTTINENQR-------------------ERILEQVENK 962

  Fly  1167 ---NIYWRSHSYHSLKNFLEGIVSEFQI 1191
               ::.|.|.....:..:|:....|.:|
 Frog   963 WRKSLGWTSKINDEILTWLQRNADEAEI 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	M1_APN-Q_like	297..764	CDD:341064	157/514 (31%)
		ERAP1_C	846..1126	CDD:463368	82/307 (27%)
lvrn	XP_031748993.1	M1_APN-Q_like	79..568	CDD:341064	156/513 (30%)
		ERAP1_C	641..945	CDD:463368	82/313 (26%)