Protein Alignment CG46339 and LOC100004744

DIOPT Version :10

• Sequence 1: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: XP_001920418.2
• Gene: LOC100004744 / 100004744
• -ID: -
• Length: 935
• Species: Danio rerio
• Alignment Length: 964
• Identity: 281/964 - (29%)
• Similarity: 467/964 - (48%)
• Gaps: 129/964 - (13%)

  Fly   280 TTKPINRPLKLY---EGWRPLHYSLLIEPSVATS-------ISNGSLTIEIERDVSKVTSWEPIV 334
            ||:....|.|.|   :...|.:|::.:.|.:...       ..|.|:..:..|:.      :.|:
Zfish    35 TTESHVEPWKEYRLPDTLFPHYYNITLWPRLQPDDHGLYVFTGNSSVVFKCLRET------DIII 93

  Fly   335 LDVHNVSISNVRVIRALADG------ASNASEEQDLDFDSDYGEDNATFVINLSKTLAVET---- 389
            :..:.:::::       .||      |.:.||...:         ..|::..:::.|.::.
Zfish    94 IHCNKLNLTS-------EDGYLAKLSAFSTSEVPSV---------KKTWIEEMTQYLVLQLNGKL 142

  Fly   390 ---QLRVLLSLDFVSQVTDTLQGIYKTSYTNPDTKNEEWMIST-QFSPVDARRAFPCFDRPDMKA 450
               :|.||.: :||.::.|.|.|:|::.|   |...|:.:::| |..|..||:.|||||.|.|||
Zfish   143 KAGELYVLYT-EFVGELADDLAGLYRSEY---DEDGEKKIVATSQMHPTHARKTFPCFDEPAMKA 203

  Fly   451 NFSISIVRPMQFKMALSNMPKSGSRRFRRGFIRD-------DFETTPKMPTYLVAFIVSNMVDSR 508
            .|.|:::.. :..:||||    |........|.|       .||.|..|.:||:|.:||:.  :.
Zfish   204 VFHITLIHD-RGTVALSN----GMEIENVDTIVDGQPVTVTTFEPTKIMSSYLLALVVSDY--TN 261

  Fly   509 LASQDSGLTPRVEIWTRPQFV--GMTHYAYKMVRKFLPYYEDFFGIKNKLPKIDLVSVPDFGFAA 571
            :.|.|..|   :.||.|.:.:  |...||..:....|.::|:::.:...|.|.|.:::|||.|.|
Zfish   262 VTSADGTL---IRIWARKKAIEDGHGDYALNITGPILKFFENYYNVPYPLSKSDQIALPDFYFGA 323

  Fly   572 MENWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHELAHQWFGNLVTPKWWDDLWLKEGFAC 636
            ||||||:.:|:|.||....:   ||:.:.:..|.||||||||.|||||||.|||:::||.||||.
Zfish   324 MENWGLVMYRESNLLYDPTV---SSNANKERTATIIAHELAHMWFGNLVTLKWWNEVWLNEGFAS 385

  Fly   637 YMSYKALEHAHPEFQSMDTLTMLEFKESMEHDADNTSHAISF---DVRSTNDVRRIFDPISYSKG 698
            |:||...:.|.|.:...|.:.:.:.......||..:||.:|.   |:.....:...||.:|||||
Zfish   386 YVSYLGADFAEPSWNVKDLIILKDVHRVFAVDALASSHPLSSKEEDIIKPEQIIEQFDTVSYSKG 450

  Fly   699 TILLRMLNSIVGDVAFRSATRDLLKKFAYGNMDRDDLWAMLTRHGHEQGT-LPKDLSVKQIMDSW 762
            ..:||||:..:.:..|.......|..||..|...:|||..|....::.|| ||  ||||.|||.|
Zfish   451 ASVLRMLSDFLTEPVFVQGLNTYLTMFADQNTVGEDLWDHLQTAVNKTGTVLP--LSVKVIMDRW 513

  Fly   763 ITQPGYPVVNVERRGADLVLRQERYLLPSKNTADQST-----WFIPITFETDELRKGDNIPTHWM 822
            :.|.|:|||.|......  :.|..:||..:::..:::     |.:||               :||
Zfish   514 VLQMGFPVVTVNTTTGQ--VSQMHFLLDPESSLQRTSPFNYEWIVPI---------------NWM 561

  Fly   823 RSED--------EEELIVGNVFAHSSNSDNVIYLNLNRQGYYRVNYDMTSW----LALKKNFSTL 875
            :|:.        |...:..::   .:.....:.||||..||||||||:.:|    ..|.:|...:
Zfish   562 KSKMVQSRFWLLERTAVYNDM---KTTGSEWVLLNLNITGYYRVNYDIGNWERLLNQLAENHKVI 623

  Fly   876 PRITRAQLLDDALHLSQAEYLTYDIPLTFLMELFDAVDDE---LLWIAAKPGLNYLIYNLKREPA 937
            ..|.|||::|||.:|::|:.    ||:|..::....:.:|   :.|.:|...|:|......:...
Zfish   624 SVINRAQIVDDAFNLARAKI----IPVTLALKTTTYLSEEREYMPWQSALNNLDYFYLMFTQTEV 684

  Fly   938 YETFRAFMKFIVRPAFDHYGLHEPD----NESHLQLKHRALVAYFACKFNYDRCTQKAQMKFREW 998
            |...:::.|..|.|.||::.....|    ...|....::.....|||....|.|.......:::|
Zfish   685 YRLLQSYTKKQVTPLFDYFKTITEDWSDVPSGHTDQYNQVNAIRFACSTGVDECQNLTSSWYKQW 749

  Fly   999 MRDPKNNPIKPNLKSVIYCTSLAEGSSPEWYFAYKQYKTTTSASEKEEILTSLGCTTKPWLLSKY 1063
            |..|.:|||.|||:|.:||:::|.|.:.||.|.:..:|  .:|.|.:::::||.|.....||.:|
Zfish   750 MDQPNHNPIHPNLRSTVYCSAIATGGAEEWDFGWTMFK--NAAIEADKLMSSLACAKNQTLLKRY 812

  Fly  1064 LNMTINPTSGILKQDGALAFRAVASNAIGHEIAFDFLQGNIKEIVEYYGDGFSTLSEMIKSLTIY 1128
            |..|::| |.|.|||.......:|||..|.::|::|::...:.:...||.|....:.:|..:|..
Zfish   813 LGYTLDP-SMIRKQDATSVIVYIASNPDGQKLAWEFVRNKWEYMFTEYGVGSFNFASLISGITKT 876

  Fly  1129 MNKDYHKHQLLDLAATCRKLGLHAVESAIELALEQVNNNIYWRSHSYHSLKNFL 1182
            .:.:....|||...:...::|..:..:|:|.|:|:...||.|.:.:...:.::|
Zfish   877 FSTEAELEQLLKFKSDNSEIGFGSATAALEQAIEKTKANIKWVAENQEDITDWL 930

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46339	NP_001263001.1	M1_APN-Q_like	297..764	CDD:341064	157/500 (31%)
		ERAP1_C	846..1126	CDD:463368	89/290 (31%)
LOC100004744	XP_001920418.2	M1_APN-Q_like	57..515	CDD:341064	157/498 (32%)
		ERAP1_C	589..914	CDD:463368	98/331 (30%)