DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment drl and YDA

DIOPT Version :9

Sequence 1:	NP_001260566.1	Gene:	drl / 44355	FlyBaseID:	FBgn0015380	Length:	645	Species:	Drosophila melanogaster
Sequence 2:	NP_001319310.1	Gene:	YDA / 842674	AraportID:	AT1G63700	Length:	883	Species:	Arabidopsis thaliana

Alignment Length:	646	Identity:	141/646 - (21%)
Similarity:	226/646 - (34%)	Gaps:	184/646 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 AVPVPANI--SDVTFT-------------------WQSLVDHPLPYSINIATSDTEVLP----RP 96
            |||:|..|  ..||.|                   |..|   |.|:.......:|...|    ..
plant    82 AVPLPRPIVRPHVTSTDSGMNGSQRPGLDANLKPSWLPL---PKPHGATSIPDNTGAEPDFATAS 143

  Fly    97 ILNISRIGDVPVEPQTWGIALKCSGTRNAEVTVTINVEVILDRATNNNTNLIFKRKKICLREEQD 161
            :.:.|.:||:|.:.....:|..|.......|.::..     |::.::|.|.....|.:..:....
plant   144 VSSGSSVGDIPSDSLLSPLASDCENGNRTPVNISSR-----DQSMHSNKNSAEMFKPVPNKNRIL 203

  Fly   162 SAHEEYDDDDLDLLQTARKGHGGDIHYVDRNDEHVVANGHQAPEKQRPVVTESPVGRGNSGGSKR 226
            ||            ...|:..|..:..:......:|.  ..||:......:.||:         |
plant   204 SA------------SPRRRPLGTHVKNLQIPQRDLVL--CSAPDSLLSSPSRSPM---------R 245

  Fly   227 DFDPMLREN---LVPPASGLVTLI------------------VGGILALVL----------VSTL 260
            .|.|....|   |:......|:|:                  :||.:|..|          .|.:
plant   246 SFIPDQVSNHGLLISKPYSDVSLLGSGQCSSPGSGYNSGNNSIGGDMATQLFWPQSRCSPECSPV 310

  Fly   261 ILIAYCAKGPSKR---------HPSNGVHLI---------KTSSFQRLP----TISSTAHNSIYV 303
            ......:.|||.|         ||..|....         ......|||    .||:|
plant   311 PSPRMTSPGPSSRIQSGAVTPLHPRAGGSTTGSPTRRLDDNRQQSHRLPLPPLLISNT------- 368

  Fly   304 CPSTITPTYATLTRPFREYEHEPEEFNRRLQELTVQK-CRVRLSCLVQEGNFGRIYRGTYNDCQE 367
            ||  .:|||:..|.|  .....|..     .|.||.. .|.:...|:..|:||.:|.|..::..|
plant   369 CP--FSPTYSAATSP--SVPRSPAR-----AEATVSPGSRWKKGRLLGMGSFGHVYLGFNSESGE 424

  Fly   368 V-LVKTVA---------QHASQLQVNLLLQESMMLYEASHPNVLSVLGI-SIEDYATPFVLYAAT 421
            : .:|.|.         :.|.||.     ||..:|....|.|::...|. :::|....::.|.:.
plant   425 MCAMKEVTLCSDDPKSRESAQQLG-----QEISVLSRLRHQNIVQYYGSETVDDKLYIYLEYVSG 484

  Fly   422 GSVRNLKSFLQD-----PSYARSVTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLR 481
            ||:..|   ||:     .:..|:.|  |.:|.|      :.:||....:|:||...|.::|...|
plant   485 GSIYKL---LQEYGQFGENAIRNYT--QQILSG------LAYLHAKNTVHRDIKGANILVDPHGR 538

  Fly   482 VKLTDSALSRDLFPGDYNSLGDGEYRPIK------WLSLEALQKSH-YNEGSDVWSFGVLMWEMC 539
            ||:.|..:::.:         ..:..|:.      |::.|.::.|: .|...|:||.|..:.||.
plant   539 VKVADFGMAKHI---------TAQSGPLSFKGSPYWMAPEVIKNSNGSNLAVDIWSLGCTVLEMA 594

  Fly   540 TLGKLPYAEIDPYE-MEHYLKDGYRLAQPFNCPDELF----TIMAYCWASMPAERPSFSQL 595
            |. |.|:::   || :....|.|.....| :.||.|.    ..:..|....||.||:.:||
plant   595 TT-KPPWSQ---YEGVPAMFKIGNSKELP-DIPDHLSEEGKDFVRKCLQRNPANRPTAAQL 650

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drl	NP_001260566.1	WIF	21..157	CDD:128745	25/124 (20%)
		PTK_Ryk	336..606	CDD:270639	73/289 (25%)
		Pkinase_Tyr	343..599	CDD:285015	70/281 (25%)
YDA	NP_001319310.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000