Protein Alignment drl and Ret

DIOPT Version :9

• Sequence 1: NP_001260566.1
• Gene: drl / 44355
• FlyBaseID: FBgn0015380
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_477044.1
• Gene: Ret / 43875
• FlyBaseID: FBgn0011829
• Length: 1235
• Species: Drosophila melanogaster
• Alignment Length: 592
• Identity: 147/592 - (24%)
• Similarity: 228/592 - (38%)
• Gaps: 148/592 - (25%)

  Fly   112 TWGIALKCSGTRNAEVTVTINVEVILDRATNNNTNLIFK-RKKICLREEQDSAHEEYDDDDLDLL 175
            ||....:.|..|      .|||.::..|..|.:..|..| |.:.|.:.:..|....|..     |
  Fly   498 TWIDQQRLSHVR------VINVHLVHGRPENTSCELKVKSRSQTCAQIKYQSQCVRYCG-----L 551

  Fly   176 QTARKGHGGDIHYVDRND------------------EHV---------------------VANGH 201
            .|.    ||...:...|.                  :||                     :...|
  Fly   552 ATG----GGSCQWRGSNSAMFGTRYGSCVPESRYCPDHVCDPLEELNPMACPQDCTPAGRIVGPH 612

  Fly   202 QAPEKQRPVVTESPV----GRGNSGGSKRDFDPMLR-----------ENLV------PPASGLVT 245
            .:.|.:|.:.:.|..    ..|....:..|.:|.::           |.|:      ||...|..
  Fly   613 SSNENKRGIYSASGTCICEDNGKCSCAPLDEEPKMKKPRKRKNETEAEPLLGVRRGTPPNQPLQD 677

  Fly   246 LIVGGILALV----------------LVSTLILIAYCAKGPSKRHPSNGVHLIKTSSFQRLPTIS 294
            .::.|:|.:.                |:..|:|:..............|...:.|||.|.||
  Fly   678 PMLLGVLNVAGFECDRSCMFFVITCPLLFVLLLLCLLIAQRKMLQRRLGKQSMTTSSKQALP--- 739

  Fly   295 STAHNSIYVCPSTITPTYATLTRPFR-EYEHEPEEFNRRLQELTVQKCRVRLSCLVQEGNFGRIY 358
            .:......:.|         |...|| |......||.|.         :::|..::.||.||::.
  Fly   740 ESGGGDFALMP---------LQSGFRFESGDAKWEFPRE---------KLQLDTVLGEGEFGQVL 786

  Fly   359 RGTYND------CQEVLVKTVAQHASQLQVNLLLQESMMLYEASHPNVLSVLGISIEDYATPFVL 417
            :|...:      ...|.||.:.:.::.::...||.|..:|.|.|||||:.:||......|...::
  Fly   787 KGFATEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLLQEVSHPNVIKLLGACTSSEAPLLII 851

  Fly   418 -YAATGSVRNLKSFLQ----------------DPSYARSVTTIQTVLMGSQLAMAMEHLHNHGVI 465
             ||..||   |:|:|:                :|...:.|.|     ...|:...|.:|....::
  Fly   852 EYARYGS---LRSYLRLSRKIECAGVDFADGVEPVNVKMVLT-----FAWQICKGMAYLSELKLV 908

  Fly   466 HKDIAARNCVIDDQLRVKLTDSALSRDLFPGDYNSLGDGEYRPIKWLSLEALQKSHYNEGSDVWS 530
            |:|:||||.::.|....|::|..|:||::..|.......:..|:||::.|:|....|...|||||
  Fly   909 HRDLAARNVLLADGKICKISDFGLTRDVYEDDAYLKRSRDRVPVKWMAPESLADHVYTSKSDVWS 973

  Fly   531 FGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQL 595
            ||||.||:.|||..||..|.|..:...||.|||:.:|.||.:.:::|:..|||..|..||||..|
  Fly   974 FGVLCWELITLGASPYPGIAPQNLWSLLKTGYRMDRPENCSEAVYSIVRTCWADEPNGRPSFKFL 1038

  Fly   596 QICLSEF 602
               .|||
  Fly  1039 ---ASEF 1042

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drl	NP_001260566.1	WIF	21..157	CDD:128745	13/45 (29%)
		PTK_Ryk	336..606	CDD:270639	93/290 (32%)
		Pkinase_Tyr	343..599	CDD:285015	90/278 (32%)
Ret	NP_477044.1	PKc_like	770..1049	CDD:304357	93/284 (33%)
		TyrKc	771..1042	CDD:197581	91/281 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455305
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940