Protein Alignment drl and Fgfr4

DIOPT Version :10

• Sequence 1: NP_001260566.1
• Gene: drl / 44355
• FlyBaseID: FBgn0015380
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: XP_006253668.1
• Gene: Fgfr4 / 25114
• RGDID: 2612
• Length: 801
• Species: Rattus norvegicus
• Alignment Length: 395
• Identity: 118/395 - (29%)
• Similarity: 180/395 - (45%)
• Gaps: 68/395 - (17%)

  Fly   244 VTLIVGGILALVLVSTLILIA--YCAKGPSKRHPSNGVHLIKTSSFQRLPTISSTAHNSIYVCPS 306
            :.|.|.|.|||||   |:|:|  |..:.....|....|.:.|.|.|......|..:.:|
  Rat   369 IILYVSGSLALVL---LLLLAGVYHRQAIHGHHSRQPVTVQKLSRFPLARQFSLESRSS------ 424

  Fly   307 TITPTYATLTRPFREYEHEPE----------------EFNRRLQELTVQKCRVRLSCLVQEGNFG 355
              ..:..:|.|..|.....|.                ||.|.         |:.|...:.||.||
  Rat   425 --GKSSLSLVRGVRLSSSGPPLLTGLVSLDLPLDPLWEFPRD---------RLVLGKPLGEGCFG 478

  Fly   356 RIYRGTY--------NDCQEVLVKTVAQHASQLQV-NLLLQESMMLYEASHPNVLSVLGISIED- 410
            ::.|...        :....|.||.:..:||...: :|:.:..||.....|.|::::||:..::
  Rat   479 QVVRAEALGMDSSRPDQTSTVAVKMLKDNASDKDLADLISEMEMMKLIGRHKNIINLLGVCTQEG 543

  Fly   411 --YATPFVLYAATGSVRNLKSFLQ---------DPSYARS----VTTIQTVLMGSQLAMAMEHLH 460
              |.  .|.|||.|   ||:.||:         .|...||    ::....|....|:|..|::|.
  Rat   544 PLYV--IVEYAAKG---NLREFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLE 603

  Fly   461 NHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFPGDYNSLGDGEYRPIKWLSLEALQKSHYNEG 525
            :...||:|:||||.::.:...:|:.|..|:|.:...||.........|:||::.|||....|...
  Rat   604 SRKCIHRDLAARNVLVTEDDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQ 668

  Fly   526 SDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERP 590
            |||||||:|:||:.|||..||..|...|:...|::|:|:.:|.|||.||:.:|..||.:.|::||
  Rat   669 SDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQRP 733

  Fly   591 SFSQL 595
            :|.||
  Rat   734 TFKQL 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drl	NP_001260566.1	WIF	21..157	CDD:128745
		PTK_Ryk	336..606	CDD:270639	92/285 (32%)
Fgfr4	XP_006253668.1	Ig	33..101	CDD:472250
		Ig strand B	50..54	CDD:409549
		Ig strand E	81..85	CDD:409549
		Ig strand F	95..100	CDD:409549
		Ig	143..237	CDD:472250
		Ig strand B	164..168	CDD:409443
		Ig strand C	177..181	CDD:409443
		Ig strand E	203..207	CDD:409443
		Ig strand F	217..222	CDD:409443
		Ig strand G	230..233	CDD:409443
		Ig	245..347	CDD:472250
		Ig strand B	263..267	CDD:409444
		Ig strand C	276..280	CDD:409444
		Ig strand E	312..316	CDD:409444
		Ig strand F	326..331	CDD:409444
		Ig strand G	339..342	CDD:409444
		Protein Kinases, catalytic domain	453..766	CDD:473864	95/300 (32%)